1-(3-Chlorobenzyl)piperazine
1-(3-Chlorobenzyl)piperazine (CAS 23145-91-7) is a substituted piperazine building block with the molecular formula C11H15ClN2 and a molar mass of 210.70 g/mol. Supplied by Tech Serve Solutions as a research-grade liquid of 98% assay, it pairs a basic piperazine ring with a 3-chlorobenzyl group, making it a versatile intermediate in heterocyclic and pharmaceutical chemical synthesis. It is a corrosive material requiring careful handling.
- Synonyms
- 1-(3-Chlorobenzyl)piperazine1-[(3-chlorophenyl)methyl]piperazine3-chlorobenzylpiperazinemeta-chlorobenzylpiperazine1-(3-chlorobenzyl)-piperazine
Pharmaceutical and medicinal-chemistry intermediate
Used as a building block in the synthesis of pharmaceutical actives and candidates. The reactive secondary amine of the piperazine ring supports N-alkylation, acylation and related coupling reactions.
Heterocyclic building block
Serves as a halogenated heterocyclic synthon for assembling more complex piperazine-containing scaffolds. The aryl chloride and the free NH provide convenient points for further functionalisation.
Fine and specialty chemical synthesis
Applied in custom and research-scale organic synthesis where a 3-chlorobenzyl-substituted piperazine motif is required. Its defined assay supports reproducible multi-step routes.
Laboratory research and process development
Suitable for laboratory-scale method development and route screening. Supplied with consistent identity and purity for analytical and synthetic work.
| Molecular weight | 210.70 |
|---|---|
| Empirical formula | C11H15ClN2 |
| Assay | 98% |
| Boiling point | 120-123 °C/1.5 mmHg(lit.)120-123 °C/1.5 mmHg |
| Density | 1.129 g/mL at 25 °C |
| Refractive index | n20/D 1.5582 |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Chlorobenzyl)piperazine used for?
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It is primarily used as a building block and intermediate in heterocyclic and pharmaceutical chemical synthesis. The piperazine NH and the 3-chlorobenzyl group allow it to be elaborated into more complex piperazine-based molecules and active pharmaceutical ingredients.
What is the CAS number and molecular formula of 1-(3-Chlorobenzyl)piperazine?
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The CAS number is 23145-91-7 and the molecular formula is C11H15ClN2 (Hill notation). The molecular weight is 210.70 g/mol and the MDL number is MFCD02048053.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(3-Chlorobenzyl)piperazine as a technical/research-grade material with a typical assay of 98%. It is supplied as a liquid (density 1.129 g/mL at 25 °C, refractive index n20/D 1.5582). We do not represent it as USP, BP or EP pharmacopoeia grade; a certificate of analysis is provided with each batch.
What are the safety and handling requirements for 1-(3-Chlorobenzyl)piperazine?
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It is classified under GHS with signal word Danger and pictograms GHS05 (corrosion) and GHS07. The hazard statements are H302 (harmful if swallowed) and H314 (causes severe skin burns and eye damage). Handle with gloves, goggles, a face shield and suitable respiratory protection, avoid contact with skin and eyes, and consult the SDS before use. The German Water Hazard Class (WGK) is 2.
How is 1-(3-Chlorobenzyl)piperazine packed, shipped and exported?
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It is packed in appropriately sealed, corrosion-resistant containers with sizes available on request. As a corrosive material it is classified for transport as UN 2735, Class 8, Packing Group III, and is shipped in compliance with applicable dangerous-goods regulations. Tech Serve Solutions exports worldwide with full documentation, including SDS and certificate of analysis.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged subject to availability and dangerous-goods shipping requirements.
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