1-(3-Aminopropyl)-4-(2-methoxyphenyl)piperazine
1-(3-Aminopropyl)-4-(2-methoxyphenyl)piperazine (CAS 20529-23-1; C14H23N3O; molar mass 249.35 g/mol) is a difunctional heterocyclic building block combining a 2-methoxyphenylpiperazine ring with a primary aminopropyl side chain. Tech Serve Solutions supplies it as a research-grade reagent at an assay of at least 97.0% (HPLC). The pendant primary amine and the substituted piperazine make it a versatile intermediate for chemical synthesis and medicinal-chemistry research.
- IUPAC
- 3-[4-(2-Methoxyphenyl)-1-piperazinyl]propylamine
- Synonyms
- 1-(3-Aminopropyl)-4-(2-methoxyphenyl)piperazine3-[4-(2-Methoxyphenyl)-1-piperazinyl]propylamine3-[4-(2-Methoxyphenyl)piperazin-1-yl]propan-1-amine4-(2-Methoxyphenyl)-1-piperazinepropanamineCAS 20529-23-1

Heterocyclic building block
Serves as a piperazine-based scaffold in multistep organic synthesis, where the 2-methoxyphenylpiperazine ring is a recurring motif in fine-chemical and medicinal-chemistry programmes.
Functionalisation through the primary amine
The terminal aminopropyl group provides a reactive handle for amidation, reductive amination, urea and sulfonamide formation, and conjugation, enabling rapid elaboration into more complex molecules.
Pharmaceutical-intermediate research
Substituted arylpiperazines are widely studied as intermediates in drug-discovery chemistry; this compound supports the preparation of candidate structures for laboratory evaluation.
Reference and laboratory reagent
Supplied at an assay of at least 97.0% (HPLC), it is suitable for synthetic, analytical and method-development work at research scale.
| Molecular weight | 249.35 |
|---|---|
| Empirical formula | C14H23N3O |
| Assay | ≥97.0% (HPLC)97% |
| Storage temperature | 2-8°C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Aminopropyl)-4-(2-methoxyphenyl)piperazine used for?
+
It is used mainly as a heterocyclic building block and intermediate in chemical synthesis and medicinal-chemistry research. Its primary aminopropyl group and 2-methoxyphenylpiperazine ring allow it to be elaborated into more complex molecules through standard amine chemistry such as amidation and reductive amination.
What is the CAS number and molecular formula of 1-(3-Aminopropyl)-4-(2-methoxyphenyl)piperazine?
+
Its CAS number is 20529-23-1 and its molecular formula is C14H23N3O, with a molecular weight of 249.35 g/mol. The Beilstein registry number is 751376.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound as a research/technical-grade reagent at an assay of at least 97.0% (HPLC). We do not represent it as a USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch.
What are the safety and handling requirements?
+
This is a corrosive substance (GHS05, signal word Danger; H314 — causes severe skin burns and eye damage). Wear protective gloves, eye and face protection, avoid contact with skin and eyes, and handle with adequate ventilation. In case of contact, rinse cautiously with water and seek medical attention. Store at 2-8°C in a tightly closed container. Always consult the Safety Data Sheet before use.
How is 1-(3-Aminopropyl)-4-(2-methoxyphenyl)piperazine packed, shipped and exported?
+
It is packed in suitable inert, tightly sealed containers sized to the order and labelled to GHS requirements. As a Class 8 corrosive material (UN 2735, packing group II) it is shipped in compliance with applicable dangerous-goods regulations. Tech Serve Solutions exports worldwide with full documentation, including the certificate of analysis and Safety Data Sheet.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, lead time, packing options and export documentation. Samples can be arranged for qualified laboratory and commercial enquiries.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis