1-(2-Thienylsulfonyl)-1H-benzotriazole
1-(2-Thienylsulfonyl)-1H-benzotriazole (CAS 394245-72-8) is a crystalline benzotriazole-based building block with the molecular formula C10H7N3O2S2 and a molar mass of 265.31 g/mol. It pairs a benzotriazole leaving group with a 2-thiophenesulfonyl moiety, making it a useful heterocyclic reagent for chemical synthesis and methodology research. Tech Serve Solutions supplies this compound to laboratory and process-development chemists worldwide as a research-grade fine chemical.
- Synonyms
- 1-(2-Thienylsulfonyl)-1H-benzotriazole1-(Thiophene-2-sulfonyl)-1H-benzotriazole1-(2-Thienylsulfonyl)benzotriazole2-(1H-Benzotriazol-1-ylsulfonyl)thiopheneCAS 394245-72-8

Heterocyclic building block
Serves as a benzotriazole-containing building block in synthetic chemistry, combining a benzotriazolyl group with a 2-thienylsulfonyl unit for the assembly of more complex molecules.
Sulfonyl transfer reagent
Benzotriazol-1-yl sulfonyl compounds are widely used as sulfonyl-group sources in organic synthesis. This reagent can act as a 2-thiophenesulfonyl donor where benzotriazole departs as the leaving group.
Chemical synthesis and methodology
Applied as an intermediate and reagent in chemical synthesis and method development, where its reactive sulfonyl handle supports functionalisation and coupling studies.
Research and discovery chemistry
Used in academic and industrial discovery laboratories for exploratory routes that benefit from a thiophene-derived sulfonyl building block.
| Molecular weight | 265.31 |
|---|---|
| Empirical formula | C10H7N3O2S2 |
| Melting point | 143-144 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Thienylsulfonyl)-1H-benzotriazole used for?
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It is used as a heterocyclic building block and sulfonyl transfer reagent in chemical synthesis. Benzotriazol-1-yl sulfonyl compounds commonly act as sulfonyl-group donors, with benzotriazole serving as the leaving group, making this reagent useful for functionalisation and methodology research.
What is the CAS number and molecular formula of 1-(2-Thienylsulfonyl)-1H-benzotriazole?
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The CAS number is 394245-72-8 and the molecular formula is C10H7N3O2S2, corresponding to a molecular weight of 265.31 g/mol. Its reported melting point is 143-144 °C.
What grade and purity does Tech Serve Solutions supply?
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We supply 1-(2-Thienylsulfonyl)-1H-benzotriazole as a research/technical-grade fine chemical for synthesis and laboratory use. We do not represent it as a USP, BP or EP pharmacopoeial grade. A current specification and certificate of analysis can be provided on request before purchase.
What are the safety and handling requirements?
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It is classified under GHS07 with the signal word Warning and hazard statements H302 (harmful if swallowed), H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, avoid dust formation, and consult the Safety Data Sheet before use.
How is 1-(2-Thienylsulfonyl)-1H-benzotriazole packed, shipped and exported?
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It is supplied in sealed, labelled containers sized to the order, from laboratory quantities upward, with full documentation. As a specialist exporter since 1998, Tech Serve Solutions arranges compliant international shipping with the relevant safety and transport paperwork.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, and our team will confirm availability, specification and lead time. Samples and a formal quotation can be arranged to support evaluation before a full order.
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