Zopiclone
Zopiclone (CAS: 43200-80-2, C17H17ClN6O3) is a nonbenzodiazepine hypnotic agent. It functions as a cyclopyrrolone derivative used for the short-term treatment of insomnia. Zopiclone acts on the central nervous system, exhibiting sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant properties. Its primary application is in clinical settings for managing sleep disorders.
- IUPAC
- 4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester,Imovane
- Synonyms
- Zopiclone

Research and Development
Used as a reference standard and research chemical in neurological and pharmacological studies. It aids in understanding sleep mechanisms and potential new therapeutic targets.
Pharmacological Investigations
Facilitates research into the mechanisms of action of hypnotic drugs and their effects on GABA receptors. Essential for in vitro and in vivo studies.
Drug Discovery
Serves as a lead compound or scaffold in the development of novel central nervous system agents. Its structure provides a basis for exploring related chemical entities.
| Molecular weight | 388.81 |
|---|---|
| Empirical formula | C17H17ClN6O3 |
| Solubility | DMSO: soluble2 mg/mLH2O: insoluble |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-62 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule IV; psychotrope; regulated under CDSA - not available from Canada |
|---|---|
| Gene Information | human ... BZRAP1(9256) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Zopiclone used for?
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Zopiclone is primarily used for the short-term treatment of insomnia. It acts as a hypnotic agent on the central nervous system.
What is the CAS number and chemical formula for Zopiclone?
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The CAS number for Zopiclone is 43200-80-2 and its empirical formula is C17H17ClN6O3.
What grade and purity does Tech Serve Solutions supply for Zopiclone?
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Tech Serve Solutions supplies Zopiclone primarily for research and development purposes. The exact purity and grade should be confirmed with our sales team, as we do not claim USP, BP, or EP grades unless explicitly stated for specific batches.
What are the safety and handling precautions for Zopiclone?
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Zopiclone is classified with GHS07 and GHS08 symbols, with a Warning signal word. It has hazard statements including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), H335 (May cause respiratory irritation), and H361 (Suspected of damaging fertility or the unborn child). Appropriate PPE, including eyeshields, gloves, and respiratory protection (N100 or P3 filters), is essential.
Is Zopiclone a controlled substance?
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Yes, Zopiclone is a controlled substance. It is classified as US DEA Schedule IV and is a psychotrope regulated under the CDSA. It is not available from Canada.
How is Zopiclone typically packed, shipped, and exported?
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Zopiclone is carefully packaged to maintain stability and safety during transit. As a global supplier, Tech Serve Solutions adheres to all international regulations for the export of fine chemicals and regulated substances.
How can I request a sample or quote for Zopiclone?
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To request a sample or a quotation for Zopiclone, please contact our dedicated sales team through the website or by phone, providing your specific requirements.
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