Zebularine

CAS 3690-10-6C9H12N2O5Biochemicals & Reagents

Zebularine (CAS: 3690-10-6), with the molecular formula C9H12N2O5 and a molecular weight of 228.20 g/mol, is a synthetic nucleoside analogue. It functions as an inhibitor of DNA methyltransferases, playing a role in epigenetic research. This compound is primarily utilized in biochemical and molecular biology research for its specific enzyme inhibitory properties, contributing to the understanding of cellular processes related to DNA methylation.

IUPAC: 1-(β-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one,2-Pyrimidone-1-β-D-riboside

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Zebularine (C9H12N2O5) — chemical structure, CAS 3690-10-6; Life Science, fine chemical supplied by Tech Serve Solutions

A to CBioactive Small MoleculesBiochemicals and ReagentsCell BiologyCytidine deaminaseEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand Substrates

01 /Applications

Epigenetic Research

Zebularine serves as a valuable tool in epigenetic studies due to its ability to inhibit DNA methyltransferases. Researchers use it to investigate the role of DNA methylation in gene regulation and cellular differentiation.

Molecular Biology

As a bioactive small molecule, Zebularine is employed in molecular biology laboratories for various experimental purposes. Its mechanism of action makes it useful for studying DNA repair pathways and cellular responses to genotoxic agents.

Biochemical Assays

This compound is utilized in biochemical assays to probe the activity of cytidine deaminase and other related enzymes. Its precise inhibitory effects allow for detailed characterization of enzyme kinetics and function.

02 /Properties

Molecular weight	228.20
Empirical formula	C9H12N2O5
Assay	≥98% (HPLC)
Form	solid
Solubility	DMSO: soluble16 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

3690-10-6

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Zebularine used for?

Zebularine is primarily used in epigenetic research, molecular biology, and biochemical assays as an inhibitor of DNA methyltransferases and cytidine deaminase.

What are the CAS number and formula for Zebularine?

The CAS number for Zebularine is 3690-10-6 and its molecular formula is C9H12N2O5.

What grade and purity does Tech Serve Solutions supply for Zebularine?

Tech Serve Solutions supplies Zebularine with a purity of ≥98% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.

What are the safety and handling precautions for Zebularine?

When handling Zebularine, it is recommended to use Eyeshields and Gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is a concern. It is classified with WGK Germany 3.

How is Zebularine shipped and exported by TSS?

Zebularine is typically stored at 2-8°C. Tech Serve Solutions, as a specialist global supplier and exporter, can arrange for the appropriate packaging and shipping for domestic and international orders.