Z-Val-Lys-Lys-Arg-4-methoxy-β-naphthylamide trihydrochloride
Z-Val-Lys-Lys-Arg-4-methoxy-β-naphthylamide trihydrochloride (CAS: 100900-15-0) is a chemical compound with the formula C42H62N10O7 · 3HCl and a molecular weight of 928.39 g/mol. Utilised as a biochemical reagent, it serves as a substrate for enzymes like Cathepsin B. This compound is valuable in biochemical research, particularly within cell biology and apoptosis studies, due to its role in enzyme activity assays and cell signalling pathways.
- IUPAC
- Z-VKKR-MNA
Enzyme Substrate
This peptide derivative functions as a fluorogenic substrate for specific proteases, such as Cathepsin B. Its cleavage releases a fluorescent product, enabling the quantification of enzyme activity in biochemical assays.
Biochemical Research
Used in studies related to apoptosis, cell cycle regulation, and cell signalling pathways. It aids researchers in understanding the role of specific proteases in biological processes.
Cell Biology Studies
Applicable in in vitro experiments investigating cellular mechanisms involving lysosomal proteases and their substrates. It provides a tool for probing enzyme function within a cellular context.
| Molecular weight | 928.39 |
|---|---|
| Empirical formula | C42H62N10O7 · 3HCl |
| Storage temperature | −20°C |
Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Val-Lys-Lys-Arg-4-methoxy-β-naphthylamide trihydrochloride used for?
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Z-Val-Lys-Lys-Arg-4-methoxy-β-naphthylamide trihydrochloride is primarily used as a fluorogenic substrate in biochemical assays, particularly for the detection and quantification of Cathepsin B activity and in studies related to apoptosis and cell signalling.
What are the CAS number and formula for Z-Val-Lys-Lys-Arg-4-methoxy-β-naphthylamide trihydrochloride?
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The CAS number is 100900-15-0 and the formula is C42H62N10O7 · 3HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research purposes. The specific assay and purity are detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for handling this product?
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This compound is classified as a Warning (GHS08) and carries the hazard statement H351 (Suspected of causing cancer). Appropriate personal protective equipment, including eyeshields and suitable gloves and respiratory protection (e.g., P100/P3 filters), must be used. Handle in a well-ventilated area and avoid dust formation.
How is this chemical packed and shipped?
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This product is typically supplied in appropriate containers for chemical transport and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or a quote?
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To request a sample or a quote for Z-Val-Lys-Lys-Arg-4-methoxy-β-naphthylamide trihydrochloride, please contact our sales department through the website or by phone.
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