Z-trans-4-Hydroxy-L-prolinol
Z-trans-4-Hydroxy-L-prolinol (CAS: 95687-41-5) is a chiral organic compound with the molecular formula C13H17NO4 and a molecular weight of 251.28 g/mol. As a derivative of the amino acid proline, it features a pyrrolidine ring with hydroxyl and hydroxymethyl substituents. This compound is valuable in chemical synthesis and research, particularly within peptide chemistry and chemical biology, serving as a building block for more complex molecules.
- IUPAC
- Benzyl (2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate

Chiral Building Block in Organic Synthesis
Utilised as a stereochemically defined precursor in the synthesis of complex organic molecules, including pharmaceuticals and natural products. Its defined stereocenters are crucial for creating specific molecular architectures.
Peptide Chemistry
Incorporated into modified peptides or peptidomimetics to introduce specific structural features or to enhance biological activity. Its proline-derived structure can influence peptide conformation.
Chemical Biology Research
Employed in studies investigating biological processes where modified amino acid structures play a role. It can serve as a probe or a component in the design of biologically active compounds.
| Molecular weight | 251.28 |
|---|---|
| Empirical formula | C13H17NO4 |
| Boiling point | 240 °C(lit.) |
| Density | 1.297 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.547(lit.) |
| Optical activity | [α]20/D −33°, c = 15 in chloroform |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-trans-4-Hydroxy-L-prolinol used for?
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Z-trans-4-Hydroxy-L-prolinol is used as a chiral building block in organic synthesis, particularly in peptide chemistry and chemical biology research for the creation of complex molecules and modified peptides.
What is the CAS number and formula for Z-trans-4-Hydroxy-L-prolinol?
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The CAS number is 95687-41-5 and the empirical formula is C13H17NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a molecular weight of 251.28 g/mol. TSS provides this product for research and development purposes; it is not supplied as USP, BP, EP, or food grade.
How should Z-trans-4-Hydroxy-L-prolinol be handled safely?
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Safety precautions include wearing eyeshields and gloves. The compound is classified under WGK-Germany 3, indicating it is hazardous to water. Handle with appropriate laboratory safety measures to avoid exposure.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, a global supplier since 1998, ensures appropriate packaging for safe transport and export of chemicals according to international regulations.
How can I request a sample or quote for Z-trans-4-Hydroxy-L-prolinol?
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Please contact the TSS sales team through our website or by phone to request a sample or a quotation for Z-trans-4-Hydroxy-L-prolinol.
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