Z-β-Dab(Fmoc)-OH
Z-β-Dab(Fmoc)-OH (CAS 349547-09-7), a protected beta-amino acid derivative with the molecular formula C27H26N2O6, is a valuable building block in chemical synthesis. Its structure incorporates a Z-protected amine and an Fmoc-protected amine, facilitating selective deprotection strategies in complex molecule assembly. This compound is primarily utilized in peptide chemistry and the synthesis of unnatural amino acid derivatives for research and development purposes.
- IUPAC
- β-Z-γ-Fmoc-L-3,4-diaminobutyric acid,γ-Fmoc-β-Z-L-3,4-diaminobutyric acid,(R)-4-(Fmoc-amino)-3-(Z-amino)butyric acid,Z-β-Dbu(Fmoc)-OH
Peptide Synthesis
Z-β-Dab(Fmoc)-OH serves as a key intermediate in the solid-phase or solution-phase synthesis of peptides. The differential protection allows for controlled sequential coupling of amino acids, enabling the construction of complex peptide sequences.
Unnatural Amino Acid Derivatives
This compound is employed in the creation of novel amino acid analogues with unique structural features. These derivatives are crucial for exploring structure-activity relationships and developing new therapeutic agents.
Chemical Biology Research
Researchers in chemical biology utilize Z-β-Dab(Fmoc)-OH to synthesize modified peptides or peptidomimetics for probing biological pathways and interactions. Its incorporation can confer specific conformational properties or functionalities.
Organic Synthesis Building Block
Beyond peptide chemistry, Z-β-Dab(Fmoc)-OH acts as a versatile chiral building block in broader organic synthesis, allowing for the introduction of a functionalized diamine moiety into target molecules.
| Molecular weight | 474.51 |
|---|---|
| Empirical formula | C27H26N2O6 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]/D +7.5±1°, c = 1 in DMF |
| Melting point | 178-181 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-β-Dab(Fmoc)-OH used for?
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Z-β-Dab(Fmoc)-OH is primarily used as a protected building block in peptide synthesis, the creation of unnatural amino acid derivatives, and in chemical biology research to synthesize modified peptides for study.
What is the CAS number and molecular formula for Z-β-Dab(Fmoc)-OH?
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The CAS number for Z-β-Dab(Fmoc)-OH is 349547-09-7, and its molecular formula is C27H26N2O6.
What grade and purity does Tech Serve Solutions supply for Z-β-Dab(Fmoc)-OH?
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Tech Serve Solutions supplies Z-β-Dab(Fmoc)-OH with an assay of ≥98.0% (HPLC). This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should Z-β-Dab(Fmoc)-OH be handled safely?
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Handling Z-β-Dab(Fmoc)-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance is classified with WGK Germany 3, indicating a high hazard.
Is Z-β-Dab(Fmoc)-OH a controlled substance?
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The provided data does not indicate that Z-β-Dab(Fmoc)-OH is a controlled substance.
How is Z-β-Dab(Fmoc)-OH packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter since 1998, ensures appropriate packaging and adherence to international shipping regulations for Z-β-Dab(Fmoc)-OH.
How can I request a sample or quote for Z-β-Dab(Fmoc)-OH?
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To request a sample or quote for Z-β-Dab(Fmoc)-OH, please contact the Tech Serve Solutions sales team through our website or directly via email or phone.
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