Z-D-β-Dab(Fmoc)-OH
Z-D-β-Dab(Fmoc)-OH (CAS: 1217471-94-7) is a chiral unnatural amino acid derivative with the molecular formula C27H26N2O6 and a molecular weight of 474.51 g/mol. This compound serves as a valuable building block in chemical biology and peptide chemistry for the synthesis of complex peptides and peptidomimetics. Its structure incorporates Fmoc protection, facilitating controlled solid-phase peptide synthesis.
- IUPAC
- β-Z-γ-Fmoc-D-3,4-diaminobutyric acid,γ-Fmoc-β-Z-D-3,4-diaminobutyric acid,(S)-4-(Fmoc-amino)-3-(Z-amino)butyric acid,Z-D-β-Dbu(Fmoc)-OH
- Synonyms
- β-Z-γ-Fmoc-D-3,4-diaminobutyric acidγ-Fmoc-β-Z-D-3,4-diaminobutyric acid(S)-4-(Fmoc-amino)-3-(Z-amino)butyric acidZ-D-β-Dbu(Fmoc)-OH
Peptide Synthesis
Utilised as a non-canonical amino acid in solid-phase peptide synthesis (SPPS) to introduce unique structural or functional properties into peptide sequences. The Fmoc protecting group allows for standard deprotection and coupling protocols.
Chemical Biology Research
Enables the construction of modified peptides for studying protein-protein interactions, enzyme inhibition, or developing peptide-based therapeutics. Its unnatural beta-amino acid structure can confer increased stability against proteolysis.
Drug Discovery
Serves as a key intermediate in the synthesis of novel drug candidates or peptidomimetics. Incorporation of Z-D-β-Dab(Fmoc)-OH can modulate a molecule's pharmacokinetic and pharmacodynamic profile.
Organic Synthesis
Acts as a chiral building block for the synthesis of complex organic molecules. The defined stereochemistry and functional groups are critical for stereoselective transformations.
| Molecular weight | 474.51 |
|---|---|
| Empirical formula | C27H26N2O6 |
| Assay | ≥98.0% (HPLC) |
| Melting point | 179-183 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-D-β-Dab(Fmoc)-OH used for?
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Z-D-β-Dab(Fmoc)-OH is primarily used as a building block in peptide synthesis and chemical biology for creating modified peptides and peptidomimetics, as well as in organic synthesis as a chiral intermediate.
What is the CAS number and molecular formula for Z-D-β-Dab(Fmoc)-OH?
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The CAS number is 1217471-94-7 and the molecular formula is C27H26N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-D-β-Dab(Fmoc)-OH with an assay of ≥98.0% (HPLC). This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Z-D-β-Dab(Fmoc)-OH be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Consult the Safety Data Sheet for detailed information.
Is Z-D-β-Dab(Fmoc)-OH a controlled substance?
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Based on the provided data, there is no indication that Z-D-β-Dab(Fmoc)-OH is a controlled substance.
How is Z-D-β-Dab(Fmoc)-OH shipped and exported?
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As a global supplier, Tech Serve Solutions exports chemicals worldwide. Shipping and handling comply with international regulations for chemical transport. Specific packaging details are available upon request.
How can I request a sample or quote for Z-D-β-Dab(Fmoc)-OH?
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To request a sample or a quotation, please use the contact form on our website or contact our sales department directly, providing the product name and CAS number (1217471-94-7).
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