Z-Asp(OtBu)-OH
Z-Asp(OtBu)-OH (CAS 5545-52-8) is a protected derivative of Aspartic Acid, featuring a tert-butyl ester protecting group on the side chain carboxyl. Its linear formula is (CH3)3CO2CCH2CH(NHCO2CH2C6H5)CO2H and it has a molecular weight of 323.34. This compound is primarily utilised in peptide synthesis and chemical biology research, serving as a building block for complex biomolecules.
- IUPAC
- N-Cbz-L-aspartic acid 4-tert-butyl ester,Z-L-Aspartic acid 4-tert-butyl ester
- Synonyms
- N-Cbz-L-aspartic acid 4-tert-butyl esterZ-L-Aspartic acid 4-tert-butyl ester

Peptide Synthesis
Used as a protected amino acid building block in solid-phase or solution-phase peptide synthesis. The tert-butyl ester protects the side-chain carboxylic acid during peptide coupling reactions.
Chemical Biology
Employed in the construction of modified peptides or peptidomimetics for studying biological processes or developing therapeutic agents. It allows for precise incorporation of aspartic acid residues with controlled side-chain functionality.
Chemical Synthesis
Serves as a versatile intermediate in organic synthesis for creating complex molecules that require an aspartic acid moiety with orthogonal protection strategies.
| Molecular weight | 323.34 |
|---|---|
| Linear formula | (CH3)3CO2CCH2CH(NHCO2CH2C6H5)CO2H |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Asp(OtBu)-OH used for?
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Z-Asp(OtBu)-OH is primarily used as a protected building block in peptide synthesis and in chemical biology research for the construction of modified peptides and complex organic molecules.
What is the CAS number and formula for Z-Asp(OtBu)-OH?
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The CAS number for Z-Asp(OtBu)-OH is 5545-52-8. The linear formula is (CH3)3CO2CCH2CH(NHCO2CH2C6H5)CO2H.
What grade and purity does Tech Serve Solutions supply for Z-Asp(OtBu)-OH?
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Tech Serve Solutions supplies Z-Asp(OtBu)-OH with a purity of ≥98.0% (TLC). This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Z-Asp(OtBu)-OH be handled safely?
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Handling Z-Asp(OtBu)-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Refer to the Safety Data Sheet for detailed handling instructions.
Is Z-Asp(OtBu)-OH a controlled substance?
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The provided data does not indicate that Z-Asp(OtBu)-OH is a controlled substance.
How is Z-Asp(OtBu)-OH packed, shipped, and exported?
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Z-Asp(OtBu)-OH is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions. Specific packaging details are available upon request.
How can I request a sample or quote for Z-Asp(OtBu)-OH?
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To request a sample or a quote for Z-Asp(OtBu)-OH, please contact our sales department via the website or by phone, providing your specific requirements.
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