Yohimbinic acid monohydrate
Yohimbinic acid monohydrate (CAS: 207801-27-2) is a chemical compound with the molecular formula C20H24N2O3 · H2O and a molecular weight of 358.43. This indole derivative is supplied by TSS for laboratory and chemical synthesis applications. It is recognised for its use in analytical methods involving yohimbine and in the radiosynthesis of adrenergic antagonists.
Analytical Standard
Used in High-Performance Liquid Chromatography with Ultraviolet-Mass Spectrometry (HPLC-UV-MS) for the quantitative analysis of yohimbine in various commercial products, such as aphrodisiacs.
Radiosynthesis
Employed in the radiosynthesis of radiolabelled compounds, specifically serving as a precursor for the alpha-2 adrenergic antagonist 11C-yohimbine.
Chemical Synthesis
Serves as a valuable building block in organic synthesis, particularly for the construction of complex heterocyclic indole structures.
| Molecular weight | 358.43 |
|---|---|
| Empirical formula | C20H24N2O3 · H2O |
| Assay | 99% |
| Optical activity | [α]25/D +142.0°, c = 1 in pyridine |
| Application | Yohimbinic acid monohydrate was used in the analysis of yohimbine in commercial aphrodisiac products by HPLC-UV-MS technique1. It was used in radiosynthesis of the α2-adrenergic antagonist 11C-yohimbine2. |
| Melting point | 267-268 °C (dec.)(lit.) |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1544 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Yohimbinic acid monohydrate used for?
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Yohimbinic acid monohydrate is utilised in analytical chemistry for the quantification of yohimbine and in radiosynthesis, particularly for producing the alpha-2 adrenergic antagonist 11C-yohimbine. It also functions as a building block in chemical synthesis.
What is the CAS number and formula for Yohimbinic acid monohydrate?
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The CAS number is 207801-27-2, and the empirical formula (Hill notation) is C20H24N2O3 · H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Yohimbinic acid monohydrate with an assay of 99%. This product is suitable for research and chemical synthesis. TSS does not represent this chemical as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should Yohimbinic acid monohydrate be handled?
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Yohimbinic acid monohydrate is classified as acutely toxic (Danger, H301-H311-H331). Handle with extreme care, using appropriate personal protective equipment including eyeshields, face shields, gloves, and a P2 respirator. Ensure adequate ventilation and avoid ingestion, skin contact, and inhalation. Refer to the Safety Data Sheet for full handling and emergency procedures.
Is Yohimbinic acid monohydrate a controlled substance?
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Based on the provided data, Yohimbinic acid monohydrate is classified as acutely toxic (T - Toxic). It is listed under UN 1544 with hazard class 6.1. Users should verify any specific national or international controlled substance regulations.
How is Yohimbinic acid monohydrate packed, shipped, and exported?
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Yohimbinic acid monohydrate is carefully packed and exported by TSS in compliance with international shipping regulations for hazardous materials, including UN 1544 classification for transport.
How can I request a quote or sample of Yohimbinic acid monohydrate?
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To request a quote or a sample of Yohimbinic acid monohydrate, please contact the TSS sales team via our website or designated contact channels, providing your specific requirements.
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