Vindoline
Vindoline (CAS: 2182-14-1, C25H32N2O6) is a monoterpenoid indole alkaloid supplied by Tech Serve Solutions. It plays a crucial role in the synthesis of important chemotherapeutic agents like vinblastine and vincristine through coupling with catharanthine. This compound is also valuable as a reference standard for its identification and purification from plant-derived materials.
- IUPAC
- Methyl (2β,3β,4β,5α,12R,19α)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methylaspidospermidine-3-carboxylate
Synthesis of Vinblastine and Vincristine
Vindoline serves as a key precursor in the semi-synthesis of vinblastine and vincristine. It is coupled with catharanthine to form these vital dimeric indole alkaloids used in chemotherapy.
Reference Standard
Utilised as a reference standard for the accurate identification and quantification of vindoline during its isolation and purification from plant sources.
Research in Alkaloid Chemistry
Its well-defined structure and biological relevance make vindoline a valuable compound for research into indole alkaloid biosynthesis and medicinal chemistry.
| Molecular weight | 456.53 |
|---|---|
| Empirical formula | C25H32N2O6 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]/D -65±3°, c = 1.5 in methanol |
| Storage temperature | 2-8°C |
| Application | Vindoline, a monoterpenoid indole alkaloid, is used to synthesize vinblastine and vincristine via coupling catharanthine. Vindoline may be used as a reference standard during its identification and purification of from plant materials. |
Hazard statements
- H341Suspected of causing genetic defects
Precautionary statements
- P281Use personal protective equipment as required
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 68 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Vindoline used for?
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Vindoline (CAS: 2182-14-1) is primarily used as a precursor in the synthesis of vinblastine and vincristine, and as a reference standard for its identification and purification from plant materials.
What are the CAS number and formula for Vindoline?
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The CAS number for Vindoline is 2182-14-1, and its empirical formula is C25H32N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Vindoline with a purity of ≥98.0% (HPLC). This is a research-grade material, and TSS does not represent it as USP, BP, or EP grade.
How should Vindoline be handled?
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Vindoline is classified as a substance that may cause genetic defects (H341). Handle with appropriate personal protective equipment (P281) in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed handling instructions.
How is Vindoline packed and shipped?
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Vindoline is typically stored at 2-8°C. Tech Serve Solutions exports fine chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Vindoline?
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Please contact our sales team through the website or by phone to request a sample or a formal quotation for Vindoline.
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