Uridine 5′-diphosphoglucuronic acid ammonium salt
Uridine 5′-diphosphoglucuronic acid ammonium salt (CAS: 43195-60-4), a vital biological molecule with the formula C15H22N2O18P2 · xNH3, serves as a key intermediate in glucuronidation pathways. It functions as a glucuronyl donor in enzymatic reactions, essential for the detoxification and elimination of various compounds in biological systems. Its primary applications are in biochemical research, drug metabolism studies, and enzymatic assays related to glycosyltransferases and PTM analysis.
- IUPAC
- UDP-GlcA,UDPGA,Uridine-diphosphate-glucuronic acid ammonium salt,Uridine[5′]diphospho[1]-α-D-glucopyranosuronic acid ammonium salt
- Synonyms
- UDP-GlcAUDPGAUridine-diphosphate-glucuronic acid ammonium saltUridine[5′]diphospho[1]-α-D-glucopyranosuronic acid ammonium salt
Biochemical Research
This compound is extensively used in research laboratories to study metabolic pathways, particularly glucuronidation, which is crucial for drug metabolism and detoxification. It serves as a substrate in enzymatic assays.
Enzymatic Assays
Uridine 5′-diphosphoglucuronic acid ammonium salt is a vital component in assays designed to measure the activity of glucuronosyltransferases and other related enzymes involved in glycan synthesis and modification.
Drug Metabolism Studies
Researchers utilize this compound to investigate how drugs and xenobiotics are metabolised in vivo and in vitro, aiding in the understanding of drug efficacy, toxicity, and clearance mechanisms.
Carbohydrate Chemistry
It plays a role in studies involving carbohydrate hydrolysis and post-translational modification (PTM) analysis, contributing to a deeper understanding of complex biological processes.
| Molecular weight | 580.29 (free acid basis) |
|---|---|
| Empirical formula | C15H22N2O18P2 · xNH3 |
| Assay | 98-100% |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Uridine 5′-diphosphoglucuronic acid ammonium salt used for?
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Uridine 5′-diphosphoglucuronic acid ammonium salt is primarily used in biochemical research, enzymatic assays, drug metabolism studies, and investigations into carbohydrate chemistry and post-translational modifications.
What is the CAS number and formula for Uridine 5′-diphosphoglucuronic acid ammonium salt?
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The CAS number is 43195-60-4, and its formula is C15H22N2O18P2 · xNH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Uridine 5′-diphosphoglucuronic acid ammonium salt with an assay of 98-100%. We do not represent this product as USP, BP, or EP grade. For specific batch purity, please refer to the Certificate of Analysis.
How should Uridine 5′-diphosphoglucuronic acid ammonium salt be handled safely?
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This compound is a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use with adequate ventilation and wear appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator if necessary. Avoid breathing dust.
How is Uridine 5′-diphosphoglucuronic acid ammonium salt packaged and shipped?
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The product is stored at -20°C. Details on specific packaging and shipping procedures for export are available upon request.
How can I request a quote or sample?
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To request a quote or sample of Uridine 5′-diphosphoglucuronic acid ammonium salt, please contact our sales team through the website or by phone.
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