URB597
URB597 (CAS: 546141-08-6), with the molecular formula C20H22N2O3 and a molecular weight of 338.40 g/mol, is a potent inhibitor of fatty acid amide hydrolase (FAAH). This bioactive small molecule is valuable in neuroscientific research for its ability to modulate neurotransmitter metabolism and signaling pathways. It has been utilised in studies investigating conditions such as stroke and epilepsy.
- IUPAC
- Cyclohexylcarbamic acid 3´-carbamoyl-biphenyl-3-yl ester
Inhibition of Fatty Acid Amide Hydrolase (FAAH)
URB597 is widely used as a selective inhibitor of FAAH, an enzyme involved in the degradation of endocannabinoids. This property makes it a crucial tool for researchers studying the endocannabinoid system and its role in various physiological processes.
Neuroscience Research
This compound has been employed in studies related to neurotransmission and neurotransmitter metabolism. Its ability to modulate the endocannabinoid system offers insights into conditions like epilepsy and the impact of ischaemic stroke on neural stem cells.
Cellular Signaling Studies
As a bioactive small molecule, URB597 is instrumental in exploring cellular signaling pathways, particularly those influenced by endocannabinoids and their metabolic enzymes. It aids in understanding cellular responses in various biological contexts.
| Molecular weight | 338.40 |
|---|---|
| Empirical formula | C20H22N2O3 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: soluble ~14 mg/mL |
| Storage temperature | 2-8°C |
| Application | URB597 has been used as a control to inhibit fatty acid amide hydrolase (FAAH) activity in mice. This study reported that URB597 can significantly potentiate anandamide-induced hypothermia1. Furthermore, studies using URB597 have reported that it can rescue elevated morbidity and mortality rates in neural stem and progenitor cell-ablated adult mice with ischaemic stroke and epilepsy2. |
Hazard statements
- H319Causes serious eye irritation
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P305IF IN EYES
- P501Dispose of contents and container per local regulations
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 22-24/25-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is URB597 used for?
+
URB597 is primarily used as a potent inhibitor of fatty acid amide hydrolase (FAAH) in research settings, particularly within neuroscience and cell biology, to study the endocannabinoid system, neurotransmission, and related conditions like stroke and epilepsy.
What is the CAS number and molecular formula for URB597?
+
The CAS number for URB597 is 546141-08-6, and its molecular formula is C20H22N2O3.
What grade and purity does Tech Serve Solutions supply for URB597?
+
Tech Serve Solutions supplies URB597 with a purity of ≥98% (HPLC). This product is intended for research purposes only and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should URB597 be handled and stored?
+
URB597 is classified as a Warning substance with hazards H319 (Causes serious eye irritation) and H410 (Very toxic to aquatic life with long lasting effects). It requires the use of eyeshields and gloves for handling and should be stored at 2-8°C. Exercise caution to avoid release into the environment.
Is URB597 a controlled substance?
+
The provided data does not indicate that URB597 is a scheduled or controlled substance. However, users should always verify local regulations.
How can I request a quote or sample for URB597?
+
To request a quote or sample for URB597, please contact our sales team through the website or by phone, referencing the product name and CAS number 546141-08-6.
How is URB597 packed and shipped?
+
URB597 is supplied as a white powder and is typically shipped under refrigeration. Specific packaging details are available upon request, and international export is available.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis