Tris(1-pyrrolidinyl)phosphine

CAS 5666-12-6C12H24N3PCatalysis & Inorganic

Tris(1-pyrrolidinyl)phosphine (CAS: 5666-12-6), with the molecular formula C12H24N3P and a molecular weight of 241.31 g/mol, is a phosphine compound. It functions as a monodentate P-donor ligand and is particularly noted for its use as a phosphitylation reagent. This chemical is supplied by Tech Serve Solutions for synthesis and research applications.

IUPAC: Phosphorous acid tripyrrolidide,Tripyrrolidinophosphine,Tris(N,N-tetramethylene)phosphorous acid triamide,Tris(N-pyrrolidinyl)phosphine,Tris(pyrrolidino)phosphine
Synonyms: Phosphorous acid tripyrrolidideTripyrrolidinophosphineTris(N,N-tetramethylene)phosphorous acid triamideTris(N-pyrrolidinyl)phosphineTris(pyrrolidino)phosphine

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Tris(1-pyrrolidinyl)phosphine (C12H24N3P) — chemical structure, CAS 5666-12-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisPhosphine CompoundsPhosphine Ligands

01 /Applications

Phosphitylation Reagent

Tris(1-pyrrolidinyl)phosphine serves as a phosphitylation reagent. It is specifically employed in the synthesis of oligonucleotides, facilitating the introduction of phosphite groups in the construction of these complex molecules.

Monodentate P-Donor Ligand

This compound acts as a monodentate phosphine ligand in coordination chemistry. Its structure allows it to coordinate to metal centres through the phosphorus atom, influencing the reactivity and properties of catalytic systems.

Chemical Synthesis

As a versatile phosphine compound, Tris(1-pyrrolidinyl)phosphine is utilised in various organic synthesis pathways. Its reactivity makes it a valuable building block or reagent for creating more complex chemical structures.

02 /Properties

Molecular weight	241.31
Empirical formula	C12H24N3P
Assay	97%
Boiling point	104 °C/0.1 mmHg(lit.)
Density	1.041 at 25 °C1.049 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.528n20/D 1.53(lit.)
Application	Monodentate P-donor ligand.Used as a phosphitylation reagent for oligonucleotide synthesis.

03 /Safety & handling

Flash point	98 °C / 208.4 °F
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

5666-12-6

MDL number

MFCD01863555

Beilstein registry

1343311

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Tris(1-pyrrolidinyl)phosphine used for?

Tris(1-pyrrolidinyl)phosphine is used as a phosphitylation reagent, notably in oligonucleotide synthesis, and functions as a monodentate P-donor ligand in catalysis and chemical synthesis.

What is the CAS number and chemical formula for Tris(1-pyrrolidinyl)phosphine?

The CAS number for Tris(1-pyrrolidinyl)phosphine is 5666-12-6, and its chemical formula is C12H24N3P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Tris(1-pyrrolidinyl)phosphine with a minimum assay of 97%. This is a technical or research grade product, and TSS does not represent it as USP, BP, or EP grade.

How should Tris(1-pyrrolidinyl)phosphine be handled?

Tris(1-pyrrolidinyl)phosphine is combustible and has a flash point of 98 °C (208.4 °F). It is classified under WGK 3 in Germany, indicating a hazard to water. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources.

How is Tris(1-pyrrolidinyl)phosphine packed, shipped, and exported?

Tris(1-pyrrolidinyl)phosphine is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations.