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Trimethyl borate

CAS 121-43-7B(OCH3)3Chemical Synthesis

Trimethyl borate (CAS: 121-43-7), with the chemical formula B(OCH3)3 and a molecular weight of 103.91 g/mol, is a colourless liquid. It is recognised as an organoborate and an organometallic reagent. It serves as a crucial intermediate in various chemical syntheses, particularly in the production of boronic acids and their derivatives, and finds utility in speciality chemical manufacturing.

IUPAC
Boric acid trimethyl ester,Methyl borate
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Trimethyl borate (B(OCH3)3) — chemical structure, CAS 121-43-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical SynthesisOrganoboratesOrganometallic Reagents
01 /Applications

Chemical Synthesis Intermediate

Trimethyl borate is widely employed as a key intermediate in organic synthesis. It is instrumental in the preparation of boronic acids and esters, which are versatile building blocks in cross-coupling reactions like Suzuki-Miyaura coupling.

Boronic Acid and Derivative Production

This compound is a primary reagent for synthesising a broad range of boronic acids and their derivatives. These organoboron compounds have significant applications in pharmaceuticals, agrochemicals, and materials science.

Organoborate Chemistry

As a simple organoborate, Trimethyl borate is used in studies and applications involving boron-oxygen bonds. Its reactivity allows for the introduction of boron moieties into organic structures.

Specialty Reagent

It functions as a speciality reagent in various industrial chemical processes where a source of boron is required under specific reaction conditions. Its properties make it suitable for controlled boron functionalisation.

02 /Properties
Molecular weight103.91
Linear formulaB(OCH3)3
Assay≥99.0% (GC)
Gradepurum
Boiling point68-69 °C(lit.)
Density0.932 g/mL at 20 °C(lit.)
Refractive indexn20/D 1.346(lit.)n20/D 1.358
Melting point−34 °C(lit.)
Vapour density3.59 (vs air)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H226Flammable liquid and vapour
  • H312Harmful in contact with skin
  • H319Causes serious eye irritation

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point-8 °C / 17.6 °F
Transport (UN / ADR)UN 2416 3 / PGII
Water hazard class (WGK, DE)1
Hazard codes (EU)Xn
Risk statements (R)10-21
Safety statements (S)23-25

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
121-43-7
MDL number
MFCD00008346
Beilstein registry
1697939
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Trimethyl borate used for?

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Trimethyl borate is primarily used as an intermediate in organic synthesis for preparing boronic acids and derivatives, and in speciality chemical manufacturing.

What is the CAS number and chemical formula for Trimethyl borate?

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The CAS number is 121-43-7 and the chemical formula is B(OCH3)3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Trimethyl borate at a minimum assay of ≥99.0% (GC) in purum grade. We do not represent this product as USP, BP, or EP.

What are the main hazards associated with Trimethyl borate?

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Trimethyl borate is a flammable liquid and vapour (H226) and is harmful if swallowed or in contact with skin (H312). It also causes serious eye irritation (H319). Appropriate personal protective equipment, including eye protection, gloves, and respiratory protection, should be used when handling this chemical.

How is Trimethyl borate packed, shipped, and exported?

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Trimethyl borate is packed in compliance with international transport regulations, including UN 2416 classification. We export globally to meet the needs of researchers and industrial clients.

How can I request a sample or quote for Trimethyl borate?

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To request a sample or a detailed quotation, please contact our sales team through the website or by phone, providing your specific requirements.

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