Triethoxy(4-methoxyphenyl)silane
Triethoxy(4-methoxyphenyl)silane (CAS: 21130-91-6) is an organosilicon compound with the molecular formula (C2H5O)3SiC6H4OCH3 and a molecular weight of 270.40 g/mol. This compound functions as a silicon-based nucleophile. It is notably employed in palladium-catalyzed cross-coupling reactions within chemical synthesis laboratories.

Palladium-Catalyzed Cross-Coupling Reactions
Triethoxy(4-methoxyphenyl)silane serves as a silicon-based nucleophile in various palladium-catalyzed cross-coupling reactions. Its reactivity allows for the formation of new carbon-carbon or carbon-heteroatom bonds.
Organosilicon Chemistry
As a trialkoxysilane derivative, this compound is a valuable reagent in organosilicon chemistry. It can be used to introduce the 4-methoxyphenylsilyl group into organic molecules, facilitating the synthesis of complex structures.
Chemical Synthesis
This reagent is utilised in diverse chemical synthesis pathways, particularly where controlled introduction of silicon-containing moieties is required. Its defined structure and reactivity make it suitable for specific synthetic transformations.
| Molecular weight | 270.40 |
|---|---|
| Linear formula | (C2H5O)3SiC6H4OCH3 |
| Assay | 97% |
| Boiling point | 128 °C/3 mmHg(lit.) |
| Density | 1.030 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.474(lit.) |
| Application | A silicon-based nucleophile shown to be reactive in Pd-catalyzed cross-coupling reactions.1 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triethoxy(4-methoxyphenyl)silane used for?
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Triethoxy(4-methoxyphenyl)silane is used as a silicon-based nucleophile in palladium-catalyzed cross-coupling reactions and in general chemical synthesis.
What is the CAS number and formula for Triethoxy(4-methoxyphenyl)silane?
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The CAS number is 21130-91-6, and its linear formula is (C2H5O)3SiC6H4OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triethoxy(4-methoxyphenyl)silane with an assay of 97%. This product is not represented as USP, BP, or EP grade.
How should Triethoxy(4-methoxyphenyl)silane be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. Depending on the ventilation, a half-mask respirator or multi-purpose combination respirator cartridge may be necessary. Refer to the Safety Data Sheet for comprehensive guidance.
Is Triethoxy(4-methoxyphenyl)silane a hazardous substance?
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Yes, Triethoxy(4-methoxyphenyl)silane is classified under GHS hazard criteria. Its WGK Germany is 3, indicating a high hazard to water. It also has a flash point of >110 °C (>230 °F).
How is Triethoxy(4-methoxyphenyl)silane packed and exported?
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This chemical is carefully packed to ensure safe transit and is available for export globally by Tech Serve Solutions.
How can I request a sample or quote for Triethoxy(4-methoxyphenyl)silane?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing your specific requirements.
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