Tributylsilane
Tributylsilane (CAS: 998-41-4), with the chemical formula [CH3(CH2)3]3SiH and a molecular weight of 200.44 g/mol, is an organosilicon compound. It functions as a valuable reducing agent in organic synthesis. Its applications include selective reductions and as a hydrogen atom source in various chemical transformations, contributing to the development of complex organic molecules.
![Tributylsilane ([CH3(CH2)3]3SiH) — chemical structure, CAS 998-41-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F998-41-4.png&w=3840&q=75)
Reducing Agent in Organic Synthesis
Tributylsilane is employed as a selective reducing agent for various functional groups, including aldehydes, ketones, and imines. It can also be used for the reduction of halides and acetals under specific reaction conditions.
Hydrogen Atom Source
This organosilicon compound serves as a convenient source of hydrogen atoms in radical-mediated reactions. It is particularly useful for dehalogenation and desilylation processes, facilitating the formation of carbon-carbon bonds.
Reagent for Desilylation
Tributylsilane can be utilized in reactions requiring the removal of silyl protecting groups. Its reactivity allows for controlled desilylation in multi-step syntheses.
| Molecular weight | 200.44 |
|---|---|
| Linear formula | [CH3(CH2)3]3SiH |
| Assay | 99% |
| Boiling point | 225-226 °C/755 mmHg(lit.) |
| Density | 0.779 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.436(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 83 °C / 181.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tributylsilane used for?
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Tributylsilane is primarily used as a reducing agent in organic synthesis and as a source of hydrogen atoms in radical reactions, including desilylation processes.
What is the CAS number and chemical formula for Tributylsilane?
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The CAS number for Tributylsilane is 998-41-4, and its chemical formula is [CH3(CH2)3]3SiH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tributylsilane with an assay of 99%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should Tributylsilane be handled safely?
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Tributylsilane is a Warning substance that causes skin irritation, serious eye irritation, and may cause respiratory irritation (H315-H319-H335). Always use appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation. Refer to the Safety Data Sheet for detailed handling instructions.
Is Tributylsilane controlled or scheduled?
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The provided data does not indicate that Tributylsilane is a controlled or scheduled substance.
How is Tributylsilane packed, shipped, or exported?
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Tributylsilane is shipped according to regulations, with a UN number of NA 1993 and Packing Group III. Specific packaging details can be provided upon request.
How can I request a sample or quote for Tributylsilane?
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To request a sample or quote for Tributylsilane, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
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