Triacetyl-β-cyclodextrin
Triacetyl-β-cyclodextrin (CAS: 23739-88-0; Formula: C84H112O56; MW: 2017.75) is a versatile acetylated derivative of beta-cyclodextrin. It functions as a cyclodextrin, capable of forming inclusion complexes with various molecules. Its applications span controlled drug release, acting as biocompatible excipients for solubilisation, and in extraction processes, making it a valuable reagent in chemical synthesis and analysis.
- IUPAC
- β-Cyclodextrin heneicosaacetate
- Synonyms
- β-Cyclodextrin heneicosaacetate
Controlled Drug Release
Triacetyl-β-cyclodextrin is investigated for its role in controlled drug release systems, particularly in the formulation of inclusion complexes. This aids in modulating the release profile of active pharmaceutical ingredients.
Biocompatible Excipients
It serves as a biocompatible excipient, enhancing the solubility and deaggregation of challenging compounds in aqueous solutions. This property is useful for improving the bioavailability of poorly soluble drugs.
Extraction and Separation
This compound is employed in extraction processes, for instance, the selective extraction of aromatic amino acids. Its complexation abilities are leveraged in various separation science applications.
Polymerization Initiation
Triacetyl-β-cyclodextrin acts as an initiator in the polymerization of cyclic esters. This application is significant in the field of polymer chemistry for synthesizing specific polyesters.
Sustained Release Formulations
It is utilized in the development of sustained release matrix tablets. This allows for the prolonged delivery of therapeutic agents, reducing the frequency of administration.
| Molecular weight | 2017.75 |
|---|---|
| Empirical formula | C84H112O56 |
| Optical activity | [α]25/D +125°, c = 1 in chloroform |
| Application | Invovled in studies of:• Controlled drug release of an inclusion complex1• Biocompatible excipients for solubilization and deaggregation of cobalt bis(dicarbollide) derivatives in water2• Extraction of aromatic amino acids3• Emulsifiers4• Polymerization initiation of cyclic esters5• Sustained release matrix tablets6 |
| Melting point | 204-206 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triacetyl-β-cyclodextrin used for?
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Triacetyl-β-cyclodextrin is used in studies for controlled drug release, as biocompatible excipients for solubilisation, extraction of aromatic amino acids, as emulsifiers, for polymerization initiation of cyclic esters, and in sustained release matrix tablets.
What are the CAS number and chemical formula for Triacetyl-β-cyclodextrin?
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The CAS number is 23739-88-0 and the chemical formula is C84H112O56.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triacetyl-β-cyclodextrin for research and technical applications. The specific grade and purity are available upon request, and TSS does not represent this product as USP/BP/EP grade.
What are the safety precautions for handling Triacetyl-β-cyclodextrin?
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When handling Triacetyl-β-cyclodextrin, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary, given its WGK Germany hazard classification of 3.
Is Triacetyl-β-cyclodextrin a controlled substance?
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The provided data does not indicate that Triacetyl-β-cyclodextrin is a controlled substance.
How is Triacetyl-β-cyclodextrin packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, handles the packing, shipping, and export of Triacetyl-β-cyclodextrin in compliance with international regulations for chemical transport.
How can I request a sample or quote for Triacetyl-β-cyclodextrin?
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To request a sample or quote for Triacetyl-β-cyclodextrin, please contact the Tech Serve Solutions sales team through our official website or by phone.
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