trans-3-Hydroxy-L-proline
trans-3-Hydroxy-L-proline (CAS: 4298-08-2), with the molecular formula C5H9NO3 and a molecular weight of 131.13 g/mol, is a non-proteinogenic amino acid derivative. This compound is recognised for its specific stereochemistry and hydroxyl group, making it a valuable building block in chemical biology and synthesis. It serves as a key intermediate in the preparation of complex organic molecules and modified peptides.
- IUPAC
- (2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid
Chemical Biology Research
Utilised as a building block in the design and synthesis of peptides and peptidomimetics with altered biological activities or stability.
Organic Synthesis Intermediate
Serves as a chiral starting material or intermediate in the multi-step synthesis of complex organic compounds and pharmaceutical candidates.
Peptide Chemistry
Incorporated into peptide sequences to introduce conformational constraints or specific functional properties, aiding in structure-activity relationship studies.
Proline Derivative Applications
Employed in research focusing on unnatural amino acid derivatives and their potential applications in medicinal chemistry and materials science.
| Molecular weight | 131.13 |
|---|---|
| Empirical formula | C5H9NO3 |
| Assay | ≥98.0% (NT) |
| Optical activity | [α]20/D −17.5±2°, c = 4% in H2O |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-3-Hydroxy-L-proline used for?
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trans-3-Hydroxy-L-proline is primarily used in chemical biology research, as an intermediate in organic synthesis, and in peptide chemistry for creating modified peptides and peptidomimetics.
What is the CAS number and formula for trans-3-Hydroxy-L-proline?
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The CAS number is 4298-08-2 and the empirical formula is C5H9NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies trans-3-Hydroxy-L-proline with an assay of ≥98.0% (NT). TSS does not represent this product as USP, BP, or EP grade.
How should trans-3-Hydroxy-L-proline be handled safely?
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Handling trans-3-Hydroxy-L-proline requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible, considering its WGK Germany rating of 3.
Does Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including trans-3-Hydroxy-L-proline.
How can I request a sample or quote for trans-3-Hydroxy-L-proline?
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To request a sample or quote for trans-3-Hydroxy-L-proline, please contact our sales department through the website or by phone.
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