trans-2-Hydroxy-β-nitrostyrene
trans-2-Hydroxy-β-nitrostyrene (CAS 3156-43-2), with a molecular formula of C8H7NO3 and a molecular weight of 165.15 g/mol, is a key organic building block. This compound is utilised as a reactant in various synthetic organic chemistry applications, including Michael-acetalization reactions, organocatalytic stereoselective Baylis-Hillman-type reactions, and catalyst-free aqueous-mediated conjugate addition reactions. TSS supplies this chemical with an assay of 97%.
- IUPAC
- 1-Hydroxy-2-(2-nitrovinyl)benzene,2-(2-Hydroxyphenyl)nitroethene,2-(2-Nitroethenyl)phenol,2-Hydroxy-β-nitrostyrene,NSC 170698,trans-2-(2-Nitrovinyl)phenol
- Synonyms
- 1-Hydroxy-2-(2-nitrovinyl)benzene2-(2-Hydroxyphenyl)nitroethene2-(2-Nitroethenyl)phenol2-Hydroxy-β-nitrostyreneNSC 170698trans-2-(2-Nitrovinyl)phenol

Michael-Acetalization Reactions
trans-2-Hydroxy-β-nitrostyrene serves as a reactant in Michael-acetalization reactions, contributing to the formation of complex organic molecules.
Baylis-Hillman-Type Reactions
This compound is employed in organocatalytic stereoselective Baylis-Hillman-type reactions, particularly when reacting with Hagemann's esters, facilitating stereocontrolled synthesis.
Conjugate Addition Reactions
It acts as a reactant in catalyst-free aqueous-mediated conjugate addition reactions, offering a greener synthetic pathway for addition chemistry.
| Molecular weight | 165.15 |
|---|---|
| Linear formula | HOC6H4CH=CHNO2 |
| Assay | 97% |
| Application | Reactant for:• Michael-acetalization reactions1• Organocatalytic stereoselective Baylis-Hillman-type reactions with Hagemann′s esters2• Catalyst-free aqueous-mediated conjugate addition reactions3 |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-36/38-50 |
| Safety statements (S) | 26-36/37-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-2-Hydroxy-β-nitrostyrene used for?
+
trans-2-Hydroxy-β-nitrostyrene is used as a reactant in Michael-acetalization reactions, organocatalytic stereoselective Baylis-Hillman-type reactions with Hagemann's esters, and catalyst-free aqueous-mediated conjugate addition reactions.
What are the CAS number and formula for trans-2-Hydroxy-β-nitrostyrene?
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The CAS number for trans-2-Hydroxy-β-nitrostyrene is 3156-43-2, and its linear formula is HOC6H4CH=CHNO2.
What grade and purity does Tech Serve Solutions supply for trans-2-Hydroxy-β-nitrostyrene?
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Tech Serve Solutions supplies trans-2-Hydroxy-β-nitrostyrene with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the main safety hazards associated with trans-2-Hydroxy-β-nitrostyrene?
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trans-2-Hydroxy-β-nitrostyrene is classified under GHS07 and GHS09 with the signal word 'Warning'. It carries hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H400 (Very toxic to aquatic life). Appropriate personal protective equipment, including a dust mask type N95, eyeshields, faceshields, and gloves, should be used.
How is trans-2-Hydroxy-β-nitrostyrene packed and shipped?
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trans-2-Hydroxy-β-nitrostyrene is shipped as UN 3077, Class 9, Packing Group III, suitable for global export.
How can I request a quote or sample for trans-2-Hydroxy-β-nitrostyrene?
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To request a quote or sample for trans-2-Hydroxy-β-nitrostyrene, please use the 'Enquire' or 'Request Sample' buttons on the product page.
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