(±)-Thiopental
(±)-Thiopental (CAS 76-75-5), a thiobarbituric acid derivative with the empirical formula C11H18N2O2S and a molecular weight of 242.34 g/mol, is a compound with applications in biological research. It has been utilised to induce transient anaesthesia in animal models, such as rats, for <i>in vivo</i> studies like NMR spectroscopy. Its properties make it a subject of interest in neurobiology and pharmacology research.
- IUPAC
- 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid,Pentothal
- Synonyms
- Pentothal

Anesthesia in Research Models
(±)-Thiopental was employed to induce temporary anaesthesia in rats, enabling <i>in vivo</i> NMR spectroscopy experiments. This application highlights its utility in physiological and pharmacological research settings.
Neuroscience Research
As a compound related to barbiturates, (±)-Thiopental is relevant in studies concerning the central nervous system. Its effects on neuronal activity are of interest to neurobiology and cell signaling research.
Pharmacological Studies
This chemical serves as a valuable tool in pharmacological investigations due to its known sedative and hypnotic properties. Researchers may utilise it to explore drug mechanisms and effects.
| Molecular weight | 242.34 |
|---|---|
| Empirical formula | C11H18N2O2S |
| Solubility | ethanol: complete50 mg/mL |
| Application | (±)-Thiopental was used to transiently anesthetize rats for in vivo NMR spectroscopy.1 |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule III; regulated under CDSA - not available from Canada |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-Thiopental used for?
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(±)-Thiopental is used in research settings, particularly for inducing transient anaesthesia in animal models for studies such as <i>in vivo</i> NMR spectroscopy. It is also relevant in neuroscience and pharmacological research.
What are the CAS number and formula for (±)-Thiopental?
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The CAS number for (±)-Thiopental is 76-75-5, and its empirical formula is C11H18N2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (±)-Thiopental. While specific assay details may vary, TSS generally provides research or technical grades. We do not represent this product as USP, BP, or EP grade unless explicitly stated. Please contact us for lot-specific details.
What are the safety considerations for handling (±)-Thiopental?
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(±)-Thiopental is classified as harmful if swallowed (H302) and requires appropriate handling. Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is (±)-Thiopental a controlled substance?
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Yes, (±)-Thiopental is a US DEA Schedule III controlled substance and is regulated under Canada's Controlled Drugs and Substances Act (CDSA). It is not available for export from Canada.
How can I request a quote or sample for (±)-Thiopental?
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To request a quote or sample of (±)-Thiopental, please contact our sales team through the website or by phone. Provide the product name and CAS number (76-75-5) in your inquiry.
What is the molecular weight of (±)-Thiopental?
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The molecular weight of (±)-Thiopental is 242.34 g/mol.
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