TGN-020
TGN-020 (CAS: 51987-99-6; C8H6N4OS) is a white to tan powder supplied by Tech Serve Solutions. With a molecular weight of 206.22 g/mol and an assay of ≥98% (HPLC), this compound serves as a valuable tool in biochemical research. It is particularly utilised in the study of cell signaling pathways, ion channels, and as a bioactive small molecule for investigating cellular responses in various biological contexts.
- IUPAC
- 2-(Nicotinamide)-1,3,4-thiadiazole,N-(1,3,4-Thiadiazol-2-yl)-3-pyridinecarboxamide,N-(1,3,4-Thiadiazol-2-yl)pyridine-3-carboxamide,N-(1,3,4-Thiadiazolyl)-m-nicotinamide
- Synonyms
- 2-(Nicotinamide)-1,3,4-thiadiazoleN-(1,3,4-Thiadiazol-2-yl)-3-pyridinecarboxamideN-(1,3,4-Thiadiazolyl)-m-nicotinamide

Investigating Cellular Responses
TGN-020 is employed as a bioactive small molecule in cell biology research. Its application allows scientists to probe cellular mechanisms, offering insights into complex biological processes at the molecular level.
Ion Channel Studies
As an inhibitor of ion pumps and voltage-gated ion channels, TGN-020 is instrumental in research focused on ion transport. It aids in understanding the function and regulation of these critical membrane proteins.
Cell Signaling Research
The compound is used in studies related to cell signaling and neuroscience. Researchers utilise TGN-020 to investigate signaling cascades and their impact on neuronal function and overall cell communication.
| Molecular weight | 206.22 |
|---|---|
| Empirical formula | C8H6N4OS |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | DMSO: ≥8 mg/mL |
| Storage temperature | room temp |
| Application | Beas2B human lung epithelial cells were treated with TGN-020 to study the effect on cigarette smoke extracts-induced CCN1 secretion.1 |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is TGN-020 primarily used for?
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TGN-020 is primarily used in research as a bioactive small molecule for studying cell biology, cell signaling, neuroscience, and ion channels, including its role as an ion pump inhibitor.
What are the CAS number and formula for TGN-020?
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The CAS number for TGN-020 is 51987-99-6, and its empirical formula (Hill notation) is C8H6N4OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies TGN-020 with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should TGN-020 be handled and stored?
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TGN-020 is classified with a GHS07 symbol and the signal word 'Warning', with hazard statement H302 (Harmful if swallowed). It should be handled with appropriate personal protective equipment in a well-ventilated area. Storage is recommended at room temperature. Refer to the Safety Data Sheet for comprehensive handling information.
Does Tech Serve Solutions export TGN-020?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including TGN-020.
How can I request a sample or quote for TGN-020?
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To request a sample or a quote for TGN-020, please contact our sales team through the provided channels on our website.
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