Tetrahydrofurfuryl chloride
Tetrahydrofurfuryl chloride (CAS: 3003-84-7), with the molecular formula C5H9ClO and a molecular weight of 120.58, is a valuable heterocyclic building block. This compound features a furan ring substituted with a chloromethyl group, making it a versatile intermediate in organic synthesis. It is primarily utilised in chemical synthesis for the construction of more complex molecules, particularly within furan chemistry.
- IUPAC
- 2-(Chloromethyl)tetrahydrofuran
- Synonyms
- 2-(Chloromethyl)tetrahydrofuran
Organic Synthesis Intermediate
Tetrahydrofurfuryl chloride serves as a reactive intermediate in the synthesis of diverse organic compounds. Its chloromethyl group readily participates in nucleophilic substitution reactions, allowing for the introduction of the tetrahydrofurfuryl moiety into various molecular structures.
Heterocyclic Chemistry
As a substituted furan derivative, this compound is employed in the field of heterocyclic chemistry. It can be used to build more complex heterocyclic systems or as a precursor to other furan-based compounds.
Research and Development
Researchers utilise Tetrahydrofurfuryl chloride in laboratory settings for exploring new synthetic pathways and developing novel chemical entities. Its specific structure lends itself to targeted chemical transformations in R&D projects.
| Molecular weight | 120.58 |
|---|---|
| Empirical formula | C5H9ClO |
| Assay | ≥97.0% (GC) |
| Boiling point | 150-151 °C(lit.)41-43 °C/11 mmHg(lit.) |
| Density | 1.11 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.455(lit.)n20/D 1.456 |
| Storage temperature | 2-8°C |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 45 °C / 113 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetrahydrofurfuryl chloride used for?
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Tetrahydrofurfuryl chloride is primarily used as an intermediate in organic synthesis and in heterocyclic chemistry for building more complex molecules, as well as in research and development.
What is the CAS number and formula for Tetrahydrofurfuryl chloride?
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The CAS number for Tetrahydrofurfuryl chloride is 3003-84-7, and its molecular formula is C5H9ClO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetrahydrofurfuryl chloride with an assay of ≥97.0% (GC). This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Tetrahydrofurfuryl chloride be handled safely?
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Tetrahydrofurfuryl chloride is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a suitable respirator, and handle in a well-ventilated area.
Is Tetrahydrofurfuryl chloride flammable?
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Yes, Tetrahydrofurfuryl chloride is a flammable liquid and vapour, with a flash point of 45 °C (113 °F).
How is Tetrahydrofurfuryl chloride packed and shipped?
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Tetrahydrofurfuryl chloride is packed and shipped in compliance with relevant regulations, including UN 1993 for transportation.
How can I request a quote or sample of Tetrahydrofurfuryl chloride?
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To request a quote or sample of Tetrahydrofurfuryl chloride, please contact the Tech Serve Solutions sales team through our website or by phone.
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