Tetrabutylammonium borohydride
Tetrabutylammonium borohydride (CAS 33725-74-5), with the linear formula (CH3CH2CH2CH2)4N(BH4) and a molecular weight of 257.31 g/mol, is a quaternary ammonium borohydride compound. It functions as a selective reducing agent in organic synthesis. Its primary applications include the reduction of β-ketoamides, β-ketoesters, and various carbohydrate derivatives, making it a valuable reagent for precise chemical transformations.

Selective Reduction of Carbonyl Compounds
Tetrabutylammonium borohydride is employed for the selective reduction of functional groups such as β-ketoamides and β-ketoesters. This reagent allows for controlled transformations within complex organic molecules.
Carbohydrate Chemistry
The compound finds utility in carbohydrate chemistry, facilitating specific reductions of carbohydrate derivatives. This aids in the synthesis of modified sugars and related compounds.
Organic Synthesis Reagent
As a specialized borohydride, it serves as a synthetic reagent in various organic chemistry research and development settings. Its quaternary ammonium structure can influence solubility and reactivity in different solvent systems.
| Molecular weight | 257.31 |
|---|---|
| Linear formula | (CH3CH2CH2CH2)4N(BH4) |
| Assay | 98% |
| Application | Selective reducing agent for β-ketoamides,1 β-ketoesters,1 and carbohydrate derivatives.2 |
| Melting point | 124-128 °C(lit.) |


Hazard statements
- H261In contact with water releases flammable gas
- H314Causes severe skin burns and eye damage
Precautionary statements
- P231Handle under inert gas
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
- P422
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3131 4.3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 15-34 |
| Safety statements (S) | 26-36/37/39-43 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetrabutylammonium borohydride used for?
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Tetrabutylammonium borohydride is used as a selective reducing agent for compounds such as β-ketoamides, β-ketoesters, and carbohydrate derivatives in organic synthesis.
What is the CAS number and formula for Tetrabutylammonium borohydride?
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The CAS number for Tetrabutylammonium borohydride is 33725-74-5 and its linear formula is (CH3CH2CH2CH2)4N(BH4).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetrabutylammonium borohydride with a purity of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should Tetrabutylammonium borohydride be handled safely?
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Tetrabutylammonium borohydride is classified as Danger with hazards H261 (In contact with water releases flammable gas) and H314 (Causes severe skin burns and eye damage). Handling requires appropriate personal protective equipment including eyeshields, face shields, gloves, and suitable respiratory protection. Work should be performed in a well-ventilated area, avoiding contact with water. Refer to the Safety Data Sheet for full details.
How is Tetrabutylammonium borohydride packed and shipped?
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This product is shipped according to UN 3131, Hazard Class 4.3, Packing Group II regulations. TSS ensures adherence to all transport and export regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or sample, please use the contact form on our website or call our sales department. Our team will assist you promptly with your inquiry.
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