Tetra(ethylene glycol) dithiol
Tetra(ethylene glycol) dithiol (CAS: 2781-02-4; C8H18O3S2) is a versatile homobifunctional polyethylene glycol derivative with terminal thiol groups. This compound, with a molecular weight of 226.36 g/mol, finds application in chemical synthesis and materials science. Its unique structure allows for crosslinking and functionalization in polymer chemistry, self-assembly processes, and the development of advanced materials for microelectronics and chemical biology.
- IUPAC
- 2,2′-[2,2′-Oxybis(ethane-2,1-diyl)bis(oxy)]diethanethiol,Diethylene glycol di(ethanethiol)
- Synonyms
- 2,2′-[2,2′-Oxybis(ethane-2,1-diyl)bis(oxy)]diethanethiolDiethylene glycol di(ethanethiol)
Chemical Synthesis
Tetra(ethylene glycol) dithiol serves as a building block in organic synthesis, enabling the introduction of dithiol functionalities into larger molecules. It is particularly useful for creating polymers and complex structures where precise spacing and flexibility are required.
Materials Science & Nanotechnology
This dithiol is employed in surface functionalization and self-assembly processes, especially for creating monolayers on gold surfaces. Its properties are valuable in developing materials for microelectronics, sensors, and advanced coatings.
Polymer Chemistry
As a homobifunctional PEG derivative, it is used in polymerisation reactions and for crosslinking polymer chains. This allows for the modification of polymer properties, such as solubility, flexibility, and adhesion, contributing to areas like PEGylation.
Chemical Biology
The thiol groups offer reactive sites for bioconjugation and the creation of specialised reagents for biological research. Its oligoethylene glycol backbone can also impart favourable biocompatibility and solubility characteristics to biomolecules.
| Molecular weight | 226.36 |
|---|---|
| Empirical formula | C8H18O3S2 |
| Assay | 97% |
| Density | 1.100 g/mL at 25 °C |
| Refractive index | n20/D 1.502 |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 22-23-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetra(ethylene glycol) dithiol used for?
+
Tetra(ethylene glycol) dithiol is used in chemical synthesis, materials science, polymer chemistry, and chemical biology. Its applications include surface functionalization, self-assembly, polymer crosslinking, and bioconjugation.
What is the CAS number and chemical formula for Tetra(ethylene glycol) dithiol?
+
The CAS number is 2781-02-4 and the chemical formula is C8H18O3S2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Tetra(ethylene glycol) dithiol with an assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Tetra(ethylene glycol) dithiol be handled and stored?
+
Tetra(ethylene glycol) dithiol is a Danger material, harmful if swallowed, causes skin irritation, causes serious eye irritation, and toxic if inhaled. It may also cause respiratory irritation. Handle with appropriate personal protective equipment in a well-ventilated area. Store at 2-8°C.
Is Tetra(ethylene glycol) dithiol a controlled substance?
+
The provided data does not indicate that Tetra(ethylene glycol) dithiol is a controlled substance.
How is Tetra(ethylene glycol) dithiol packed and exported?
+
Tech Serve Solutions exports chemicals globally, adhering to all necessary shipping regulations for hazardous materials. Specific packing details can be provided upon request.
How can I request a quote or sample for Tetra(ethylene glycol) dithiol?
+
To request a quote or sample, please contact the TSS sales team via our website or direct contact details, specifying the product name and CAS number.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis