Testosterone β-D-glucuronide sodium salt
Testosterone β-D-glucuronide sodium salt (CAS: 4145-59-9; Formula: C25H35O8Na) is a biochemically significant androgen derivative. This compound is primarily utilised as a substrate in drug metabolism assays, particularly those involving UDP-glucuronyltransferase activity. Its role in understanding steroid hormone conjugation and metabolism makes it a valuable reagent for research in endocrinology and pharmacology. TSS supplies this compound for laboratory and research applications.
- IUPAC
- 17β-Hydroxy-4-androsten-3-one 17-D-glucuronide,4-Androsten-17β-ol-3-one 17-glucuronide
- Synonyms
- 17β-Hydroxy-4-androsten-3-one 17-D-glucuronide4-Androsten-17β-ol-3-one 17-glucuronide
Drug Metabolism Studies
Serves as a substrate for UDP-glucuronyltransferase in in vitro assays, aiding the study of testosterone glucuronidation pathways. This is crucial for understanding drug metabolism and detoxification processes.
Endocrinology Research
Used in research settings to investigate the metabolic fate and biological activity of androgenic steroids. Its conjugated form helps in understanding hormone regulation and excretion.
Biochemical Assays
Applicable in various biochemical assays requiring a well-defined steroid conjugate. Useful for enzyme kinetics and mechanism-of-action studies related to steroid metabolism.
| Molecular weight | 486.53 |
|---|---|
| Linear formula | C25H35O8Na |
| Solubility | ethanol: water (1:1): soluble10 mg/mL, clear, colorless |
| Storage temperature | −20°C |
| Application | Testosterone has been used as a substrate for UDP-glucuronyltransferase-based drug metabolism assays using microsome-encapsulation techniques1. |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H351Suspected of causing cancer
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Canada |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Testosterone β-D-glucuronide sodium salt used for?
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Testosterone β-D-glucuronide sodium salt is primarily used as a substrate in drug metabolism assays, specifically for studying UDP-glucuronyltransferase activity. It also finds application in endocrinology and biochemical research concerning androgenic steroids.
What are the CAS number and chemical formula?
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The CAS number for Testosterone β-D-glucuronide sodium salt is 4145-59-9, and its chemical formula is C25H35O8Na.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Testosterone β-D-glucuronide sodium salt for research and laboratory use. The specific grade and purity are available upon request and are not represented as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling precautions for this compound?
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This compound is classified as harmful if swallowed, in contact with skin, or if inhaled, and is suspected of causing cancer (H302, H312, H332, H351). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be used during handling. Store at -20°C.
Is Testosterone β-D-glucuronide sodium salt a controlled substance?
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Yes, this compound is controlled under USDEA Schedule III, Home Office Schedule 4.2, and is regulated under CDSA (not available from Canada).
How can I request a sample or quote for Testosterone β-D-glucuronide sodium salt?
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To request a sample or quote, please contact the Tech Serve Solutions sales team with your specific requirements.
How is Testosterone β-D-glucuronide sodium salt packed and exported?
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Testosterone β-D-glucuronide sodium salt is carefully packed to ensure stability during transport and is available for global export. Please contact us for detailed shipping and export information.
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