tert-Butyldiphenylphosphine
Tert-Butyldiphenylphosphine (CAS: 6002-34-2) is an organophosphorus compound with the linear formula (C6H5)2PC(CH3)3 and a molecular weight of 242.30 g/mol. This phosphine ligand is primarily utilised as a catalyst or ligand in various chemical synthesis reactions. Its applications span cross-coupling reactions, hydrocarboxylation, and stereoselective silylations, making it a valuable reagent in organic and inorganic chemistry research and development.
- IUPAC
- NSC 244302
Catalysis in Organic Synthesis
Tert-Butyldiphenylphosphine serves as a crucial ligand and catalyst in numerous organic transformations. It facilitates nickel or palladium-catalyzed reactions such as carbocyanation of alkynes and hydrocarboxylation of acetylene under mild conditions.
Cross-Coupling Reactions
This phosphine compound is employed as a ligand in palladium-catalyzed cross-coupling reactions. It plays a role in forming catalysts for methoxycarbonylation and other carbon-carbon bond-forming processes.
Stereoselective Transformations
The compound is utilized in stereoselective synthesis, including palladium-catalyzed stereoselective silylation via dehydrogenative Si-O coupling with chiral silanes.
Reductive Coupling Reactions
It acts as a ligand in ruthenium-catalyzed transfer hydrogenation, specifically in the reductive coupling of disubstituted allenes with aldehydes.
| Molecular weight | 242.30 |
|---|---|
| Linear formula | (C6H5)2PC(CH3)3 |
| Assay | 97% |
| Boiling point | 144-146 °C/2 mmHg(lit.) |
| Application | Catalyst for:• Nickel/Lewis acid-catalyzed carbocyanation of alkynes with acetonitrile or substituted acetonitriles1• Palladium catalyzed hydrocarboxylation of acetylene with carbon monoxide to acrylic acid under mild conditions2• Palladium to form a catalyst for methoxycarbonylation reactions3• Ru-catalyzed transfer hydrogenation in reductive coupling of disubstituted allenes with aldehydes4• Stereoselective silylation by dehydrogenative Si-O coupling with Si-stereogenic silanes5• Phosphine ligand in nickel-catalyzed carbocyanation of alkynes6• Monodentate P-Donor Ligands (LKB-P)7 |
| Melting point | 52-57 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is tert-Butyldiphenylphosphine used for?
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Tert-Butyldiphenylphosphine is primarily used as a ligand and catalyst in various organic synthesis reactions, including carbocyanation, hydrocarboxylation, methoxycarbonylation, and stereoselective silylation.
What are the CAS number and chemical formula for tert-Butyldiphenylphosphine?
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The CAS number for tert-Butyldiphenylphosphine is 6002-34-2, and its linear formula is (C6H5)2PC(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies tert-Butyldiphenylphosphine with an assay of 97%. This product is suitable for research and general chemical synthesis purposes. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should tert-Butyldiphenylphosphine be handled and stored?
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Tert-Butyldiphenylphosphine is a combustible solid with a high flash point (>110 °C). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a respirator. Store in a cool, dry, well-ventilated area away from ignition sources.
Is tert-Butyldiphenylphosphine a controlled substance?
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Based on the provided data, tert-Butyldiphenylphosphine (CAS: 6002-34-2) is not listed as a controlled substance. However, always comply with local regulations regarding its use and handling.
How can I request a quote or sample for tert-Butyldiphenylphosphine?
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To request a quote or sample, please contact our sales team through the website or by phone. Please specify the quantity required and your delivery location.
How is tert-Butyldiphenylphosphine shipped from TSS?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Tert-Butyldiphenylphosphine is packed and shipped in compliance with international shipping regulations for chemical products.
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