tert-Butyl(chloro)diphenylsilane

CAS 58479-61-1(CH3)3CSi(C6H5)2ClChemical Synthesis

Tert-Butyl(chloro)diphenylsilane (CAS 58479-61-1), with the linear formula (CH3)3CSi(C6H5)2Cl and a molecular weight of 274.86 g/mol, is a versatile silicon-based compound. It serves as a key reagent in chemical synthesis, particularly in organic chemistry. Its primary application lies in its role as a protecting group for alcohols, offering robust protection under various reaction conditions. TSS supplies this chemical for research and synthesis purposes.

IUPAC: tert-Butyldiphenylchlorosilane,TBDPSCl
Synonyms: tert-ButyldiphenylchlorosilaneTBDPSClChlorodiphenyl(tert-butyl)silane

Email us

tert-Butyl(chloro)diphenylsilane ((CH3)3CSi(C6H5)2Cl) — chemical structure, CAS 58479-61-1; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisSilicon-BasedSynthetic Reagents

01 /Applications

Protecting Group for Alcohols

Tert-Butyl(chloro)diphenylsilane is widely used to introduce the tert-butyldiphenylsilyl (TBDPS) protecting group onto primary and secondary alcohols. This protection is stable to many reagents and conditions, facilitating complex synthetic routes.

Organic Synthesis Intermediate

As a valuable intermediate, this chlorosilane enables the selective functionalisation of molecules. It is instrumental in multi-step syntheses where orthogonal protection strategies are required.

Reagent in Silicon Chemistry

This compound is a foundational reagent in the development of new silicon-containing materials and organosilicon compounds. Its reactivity allows for further derivatization and incorporation into larger structures.

02 /Properties

Molecular weight	274.86
Linear formula	(CH3)3CSi(C6H5)2Cl
Assay	≥97.0% (GC)
Boiling point	90 °C/0.01 mmHg(lit.)
Density	1.057 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.567n20/D 1.568(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	112 °C / 233.6 °F
Transport (UN / ADR)	UN 2987 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34-37
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

58479-61-1

MDL number

MFCD00000497

PubChem substance

24851910

Beilstein registry

644023

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Tert-Butyl(chloro)diphenylsilane used for?

Tert-Butyl(chloro)diphenylsilane is primarily used as a protecting group reagent in organic synthesis, particularly for protecting alcohols. It also serves as an intermediate in chemical synthesis and in the field of silicon chemistry.

What is the CAS number and formula for Tert-Butyl(chloro)diphenylsilane?

The CAS number is 58479-61-1, and its linear formula is (CH3)3CSi(C6H5)2Cl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Tert-Butyl(chloro)diphenylsilane with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, or EP grade.

How should Tert-Butyl(chloro)diphenylsilane be handled safely?

This compound is corrosive and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection. Ensure adequate ventilation and refer to the Safety Data Sheet for detailed guidance.

How is Tert-Butyl(chloro)diphenylsilane packed, shipped, and exported?

Tert-Butyl(chloro)diphenylsilane is typically packed in accordance with international transport regulations for hazardous materials. TSS offers expert export services to clients worldwide.

How can I request a sample or quote for Tert-Butyl(chloro)diphenylsilane?

To request a sample or a quotation, please contact our sales department through the website or call us directly. Provide the product name and CAS number for prompt service.