sec-Butylzinc bromide solution
Sec-Butylzinc bromide solution (CAS: 171860-66-5) is an organozinc halide with the linear formula C4H9ZnBr and a molecular weight of 202.41 g/mol. Supplied as a 0.5 M solution in Tetrahydrofuran (THF) at 25 °C, this reagent is flammable and may form explosive peroxides. It is primarily utilised in organic synthesis as a versatile organometallic reagent for carbon-carbon bond formation reactions.
Organic Synthesis
Sec-Butylzinc bromide is a valuable nucleophilic reagent in organic synthesis, enabling the formation of new carbon-carbon bonds through various cross-coupling reactions, such as Negishi couplings. Its reactivity profile makes it suitable for introducing sec-butyl groups into complex molecular architectures.
Organometallic Chemistry
As an organozinc halide, this compound is a key player in organometallic chemistry. It serves as a precursor or reagent in reactions that require a well-defined organozinc species for controlled synthetic transformations.
Pharmaceutical Intermediate Synthesis
The controlled introduction of alkyl groups is crucial in the synthesis of many pharmaceutical intermediates. Sec-Butylzinc bromide can be employed in multi-step syntheses where specific functionalisation is required.
| Molecular weight | 202.41 |
|---|---|
| Linear formula | C2H5CH(CH3)ZnBr |
| Density | 0.968 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is sec-Butylzinc bromide solution used for?
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Sec-Butylzinc bromide solution (CAS: 171860-66-5) is primarily used as an organometallic reagent in organic synthesis, particularly for forming carbon-carbon bonds and introducing sec-butyl groups into molecules, often in cross-coupling reactions.
What are the CAS number and formula for sec-Butylzinc bromide solution?
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The CAS number for sec-Butylzinc bromide solution is 171860-66-5. Its linear formula is C4H9ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies sec-Butylzinc bromide solution as a 0.5 M concentration in THF. TSS does not represent this product as USP/BP/EP or any other pharmacopoeia grade.
How should sec-Butylzinc bromide solution be handled safely?
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Sec-Butylzinc bromide solution is highly flammable (Flash Point -17 °C) and may form explosive peroxides. It is also a skin, eye, and respiratory irritant. Handle in a well-ventilated area, away from ignition sources, using appropriate personal protective equipment. Store refrigerated at 2-8°C. Consult the Safety Data Sheet (SDS) before use.
Is sec-Butylzinc bromide solution a controlled substance?
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The provided data does not indicate that sec-Butylzinc bromide solution is a controlled substance.
How is sec-Butylzinc bromide solution shipped and exported?
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Sec-Butylzinc bromide solution is classified under UN 2924, Hazard Class 8 (Corrosive) with subsidiary hazard class 3 (Flammable Liquid), Packing Group II. Tech Serve Solutions can export this product globally, adhering to all relevant shipping regulations for hazardous materials.
How can I request a sample or quote for sec-Butylzinc bromide solution?
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To request a sample or a quote for sec-Butylzinc bromide solution, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
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