Saccharin
Saccharin (CAS: 81-07-2), with the empirical formula C7H5NO3S and a molecular weight of 183.18 g/mol, is a key organic compound. It is primarily recognised for its use in chemical synthesis and as a building block in the development of more complex molecules. Its heterocyclic structure makes it valuable in various research and development applications within the chemical industry.
- IUPAC
- 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide,2-Sulfobenzoic acid imide,o-Benzoic sulfimide
- Synonyms
- 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide2-Sulfobenzoic acid imideo-Benzoic sulfimide

Synthesis of Adefovir Dipivoxil–Saccharin Cocrystal
Saccharin has been employed in the synthesis and characterisation of novel cocrystals, specifically the adefovir dipivoxil–saccharin cocrystal, contributing to the study of crystalline solid forms.
Analytical Chemistry Reagent
It serves as a reagent in analytical methods, such as a time-resolved lanthanide-sensitised luminescence technique for the simultaneous determination of benzoic acid and saccharin in food samples.
Heterocyclic Building Block
As a heterocyclic building block, saccharin is utilised in organic synthesis for constructing more complex molecular architectures, particularly those involving thiazole rings.
| Molecular weight | 183.18 |
|---|---|
| Empirical formula | C7H5NO3S |
| Assay | ≥98% |
| Solubility | H2O: soluble1g in 290mlacetone: soluble1g in 12mlalcohol: soluble1g in 31mlboiling water: soluble1g in 25mlglycerol: soluble1g in 50mlalcohol: very slightly solublechloroform: slightly solublediethyl ether: slightly soluble |
| Application | Saccharin was used in the synthesis and characterization of the novel adefovir dipivoxil–saccharin cocrystal1. It was used to develop a time resolved lanthanide-sensitized luminescence method for the simultaneous determination of benzoic acid and saccharin in food samples2. |
| Melting point | 226-229 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3077 9/PG 3 |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Saccharin used for?
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Saccharin is used as a building block in chemical synthesis, for developing novel cocrystals, and as a reagent in analytical chemistry methods for determining specific compounds in samples.
What is the CAS number and chemical formula for Saccharin?
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The CAS number for Saccharin is 81-07-2 and its empirical formula is C7H5NO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Saccharin with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade.
How is Saccharin shipped and handled?
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Saccharin is classified under UN 3077, Hazard Class 9, Packing Group III. When handling, use appropriate personal protective equipment including eyeshields, gloves, and a P1 (EN143) or N95 (US) respirator filter.
How can I request a quote or sample for Saccharin?
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To request a quote or a sample of Saccharin, please contact the Tech Serve Solutions sales team through our website or by phone.
What are the solubility characteristics of Saccharin?
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Saccharin exhibits varied solubility; it is soluble in water (1g/290ml), acetone (1g/12ml), and boiling water (1g/25ml), with lower solubility in alcohol, chloroform, and diethyl ether.
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