(+)-S-Trityl-L-cysteine
(+)-S-Trityl-L-cysteine (CAS: 2799-07-7) is a protected amino acid derivative with the linear formula (C6H5)3CSCH2CH(NH2)CO2H and a molecular weight of 363.47 g/mol. This compound is primarily utilised as a protected cysteine building block in peptide synthesis, offering a stable yet cleavable protecting group for the thiol functionality. Its optical activity, [α]25/D +115°, is a key characteristic for chiral applications in chemical biology and synthesis.
- IUPAC
- S-Trityl-L-cysteine
Peptide Synthesis
(+)-S-Trityl-L-cysteine is a crucial intermediate in solid-phase and solution-phase peptide synthesis. The trityl group effectively protects the cysteine thiol from unwanted side reactions during peptide chain elongation, and can be selectively removed under mild acidic conditions.
Chemical Biology
This compound serves as a valuable reagent in chemical biology for the synthesis of modified peptides or proteins. It enables the introduction of cysteine residues with a readily removable thiol protection, facilitating specific labelling or conjugation strategies.
Organic Synthesis
As a derivative of L-cysteine, S-Trityl-L-cysteine finds application in various organic synthesis pathways where precise control over the amino acid's functional groups is required, particularly in the construction of complex chiral molecules.
| Molecular weight | 363.47 |
|---|---|
| Linear formula | (C6H5)3CSCH2CH(NH2)CO2H |
| Assay | 97% |
| Optical activity | [α]25/D +115°, c = 0.8 in 0.04 M ethanolic HCl |
| Application | Protected cysteine for peptide synthesis. |
| Melting point | 182-183 °C (dec.)(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-S-Trityl-L-cysteine used for?
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(+)-S-Trityl-L-cysteine is predominantly used as a protected cysteine derivative in peptide synthesis and chemical biology for introducing cysteine residues into peptide chains with a protected thiol group.
What is the CAS number and chemical formula for (+)-S-Trityl-L-cysteine?
+
The CAS number for (+)-S-Trityl-L-cysteine is 2799-07-7. The linear formula is (C6H5)3CSCH2CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply for (+)-S-Trityl-L-cysteine?
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Tech Serve Solutions supplies (+)-S-Trityl-L-cysteine with an assay of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should (+)-S-Trityl-L-cysteine be handled safely?
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As indicated by GHS07, (+)-S-Trityl-L-cysteine is classified as Warning with hazard statement H302 (Harmful if swallowed). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Avoid breathing dust and ensure adequate ventilation.
Does Tech Serve Solutions export (+)-S-Trityl-L-cysteine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (+)-S-Trityl-L-cysteine.
How can I request a sample or quote for (+)-S-Trityl-L-cysteine?
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To request a sample or a quotation for (+)-S-Trityl-L-cysteine, please contact our sales team through the website or by phone, providing your specific requirements.
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