(S,S′,R,R′)-TangPhos

CAS 470480-32-1RChemical Synthesis

(S,S′,R,R′)-TangPhos (CAS: 470480-32-1), a chiral diphospholane ligand with the empirical formula C16H32P2 and a molecular weight of 286.37 g/mol, is a highly effective catalyst component. It is instrumental in achieving high enantioselectivities in various transition metal-catalyzed asymmetric synthesis reactions, particularly those involving rhodium. Its utility spans crucial transformations in organic chemistry.

IUPAC: (1S,1S′,2R,2R′)-1,1′-Di-tert-butyl-(2,2′)-diphospholane
Synonyms: (1S,1S′,2R,2R′)-1,1′-Di-tert-butyl-(2,2′)-diphospholaneR&#8242)-TangPhos

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(S,S′,R,R′)-TangPhos (R) — chemical element, CAS 470480-32-1; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand Reagents

01 /Applications

Asymmetric Hydrogenation

Highly efficient in rhodium-catalyzed hydrogenation of α-dehydroamino acids, α-arylenamides, β-(acylamino)acrylates, itaconic acids, and enol acetates, delivering excellent enantioselectivity.

Asymmetric Hydroformylation

Provides outstanding enantioselectivities in asymmetric hydroformylation reactions, making it valuable for the synthesis of chiral aldehydes.

Chiral Catalyst Ligand

Serves as a key chiral ligand in homogeneous catalysis for asymmetric synthesis, enabling the production of enantiomerically enriched compounds.

02 /Properties

Molecular weight	286.37
Empirical formula	C16H32P2
Application	Highly efficient in rhodium-catalyzed hydrogenation of α-dehyroamino acids and α-arylenamides,6 β-(acylamino)acrylates,7 itaconic acids, and enol acetates.8 Also gives outstanding enantioselectivities in asymmetric hydroformylation reactions.9
Melting point	60-65 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

470480-32-1

PubChem substance

24883788

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S,S′,R,R′)-TangPhos used for?

(S,S′,R,R′)-TangPhos is a chiral ligand used in transition metal-catalyzed asymmetric synthesis, notably in rhodium-catalyzed hydrogenation and hydroformylation reactions to achieve high enantioselectivities.

What is the CAS number and formula for (S,S′,R,R′)-TangPhos?

The CAS number for (S,S′,R,R′)-TangPhos is 470480-32-1, and its empirical formula is C16H32P2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S,S′,R,R′)-TangPhos typically as a research or technical grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated on the Certificate of Analysis.

How should (S,S′,R,R′)-TangPhos be handled?

When handling (S,S′,R,R′)-TangPhos, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used for respiratory protection. It is classified with a WGK (Germany) of 3.

How is (S,S′,R,R′)-TangPhos packed, shipped, and exported?

(S,S′,R,R′)-TangPhos is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions, a trusted supplier since 1998.

How can I request a sample or quote for (S,S′,R,R′)-TangPhos?

To request a sample or a quote for (S,S′,R,R′)-TangPhos, please contact our sales team through the website or by phone, providing your specific requirements.