(S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II)
(S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II), CAS 188264-84-8, with the linear formula [[[(CH3)3C]2C6H2-2-(O-)CH=N]2C6H10]Co and a molecular weight of 603.74, is a chiral cobalt complex. It functions as a key catalyst in asymmetric synthesis, particularly for the hydrolytic kinetic resolution of terminal epoxides and the enantioselective ring opening of meso epoxides, enabling the production of chiral building blocks.
- Synonyms
- [[[(CH3)3C]2C6H2-2-(O-)CH=N]2C6H10]Co
Hydrolytic Kinetic Resolution of Terminal Epoxides
This cobalt complex is effectively employed as a catalyst to selectively react with one enantiomer of a terminal epoxide in the presence of water. This process allows for the isolation of the unreacted, enantiomerically enriched epoxide or the corresponding chiral diol.
Enantioselective Ring Opening of Meso Epoxides
The compound serves as a valuable catalyst for the asymmetric ring opening of meso epoxides. This reaction generates chiral vicinal diols with high enantiomeric excess, which are important intermediates in organic synthesis.
Chiral Catalyst in Asymmetric Synthesis
As a chiral ligand complex, it facilitates a range of asymmetric transformations. Its structure is well-suited for promoting stereoselective reactions, making it a privileged catalyst in the synthesis of enantiomerically pure compounds.
| Molecular weight | 603.74 |
|---|---|
| Linear formula | [[[(CH3)3C]2C6H2-2-(O-)CH=N]2C6H10]Co |
| Application | Catalyst for the hydrolytic kinetic resolution of terminal epoxides1 and the enantioselective ring opening of meso epoxides.2 |
| Melting point | >350 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P312Call a POISON CENTER if you feel unwell
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) used for?
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(S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) is used as a catalyst for the hydrolytic kinetic resolution of terminal epoxides and the enantioselective ring opening of meso epoxides, crucial processes in asymmetric synthesis.
What are the CAS number and formula for this chemical?
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The CAS number is 188264-84-8, and the linear formula is [[[(CH3)3C]2C6H2-2-(O-)CH=N]2C6H10]Co.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research or technical grade material. We do not represent it as USP, BP, EP, or any other pharmacopoeial standard unless explicitly stated in the product specifications.
What are the safety and handling considerations?
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This compound is classified as Danger, with hazards including H302 (Harmful if swallowed), H311 (Toxic in contact with skin), and H332 (Harmful if inhaled). Appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves, must be used. Handle in a well-ventilated area. Dispose of as hazardous waste according to local regulations.
How is this product packed, shipped, and exported?
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Tech Serve Solutions carefully packs and ships chemicals globally, adhering to all international shipping regulations for hazardous materials. We export a wide range of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or a quote for this product?
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To request a sample or a quote, please contact our sales department through the website or by phone. Our team will be happy to assist you with your specific requirements.
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