(S)-3-Pyrrolidinol
(S)-3-Pyrrolidinol (CAS: 100243-39-8) is a chiral heterocyclic compound with the molecular formula C4H9NO and a molecular weight of 87.12 g/mol. This enantiomerically pure building block is a valuable intermediate in asymmetric synthesis. It is frequently employed in the development of complex organic molecules, particularly within the pharmaceutical and agrochemical industries, owing to its chiral nature and reactive hydroxyl group. TSS supplies this compound for research and development purposes.
- IUPAC
- (S)-3-Hydroxypyrrolidine
Chiral Building Block in Asymmetric Synthesis
(S)-3-Pyrrolidinol serves as a crucial chiral synthon for constructing enantiomerically enriched molecules. Its stereogenic centre allows for the introduction of specific chirality into target compounds, essential for the synthesis of stereospecific pharmaceuticals and other biologically active molecules.
Pharmaceutical Intermediate
This pyrrolidine derivative is utilised in the synthesis pathways for various active pharmaceutical ingredients (APIs). Its structural features are incorporated into drug candidates targeting a range of therapeutic areas, demanding precise stereochemical control.
Agrochemical Synthesis
The compound finds application in the development of novel agrochemicals, where chirality can significantly influence biological activity and selectivity. It acts as a key intermediate in the production of advanced crop protection agents.
Research and Development
As a versatile heterocyclic building block, (S)-3-Pyrrolidinol is an important reagent for organic chemists engaged in exploratory synthesis and methodology development in academic and industrial research settings.
| Molecular weight | 87.12 |
|---|---|
| Empirical formula | C4H9NO |
| Assay | ≥97.0% (sum of enantiomers, GC) |
| Density | 1.078 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.490 |
| Optical activity | [α]20/D −6.5±1.5°, c = 3.5% in methanol |
| Optical purity | enantiomeric ratio: ≥98:2 (GC) |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-3-Pyrrolidinol used for?
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(S)-3-Pyrrolidinol is primarily used as a chiral building block in asymmetric synthesis, a key intermediate in the pharmaceutical and agrochemical industries, and for general research and development in organic chemistry.
What is the CAS number and formula for (S)-3-Pyrrolidinol?
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The CAS number for (S)-3-Pyrrolidinol is 100243-39-8, and its molecular formula is C4H9NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-3-Pyrrolidinol with an assay of ≥97.0% (sum of enantiomers, GC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should (S)-3-Pyrrolidinol be handled safely?
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Warning: (S)-3-Pyrrolidinol is a skin, eye, and respiratory irritant (H315-H319-H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure good ventilation and avoid inhalation of vapours.
How is (S)-3-Pyrrolidinol typically packaged and exported?
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(S)-3-Pyrrolidinol is packaged in suitable containers to ensure stability during transport and storage. Tech Serve Solutions is a global supplier and exporter, adhering to international shipping regulations for chemical products.
How can I request a sample or quote for (S)-3-Pyrrolidinol?
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To request a sample or a quote for (S)-3-Pyrrolidinol, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements and shipping details.
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