(S)-(+)-2-[2-(Diphenylphosphino)phenyl]-4-phenyl-2-oxazoline
(S)-(+)-2-[2-(Diphenylphosphino)phenyl]-4-phenyl-2-oxazoline (CAS 148461-15-8, C27H22NOP) is a chiral phosphine-oxazoline ligand. With a molecular weight of 407.44 g/mol, it is a key component in asymmetric synthesis, particularly for catalytic applications. This compound is valued for its ability to facilitate stereoselective transformations, making it an important reagent for chemists engaged in the synthesis of enantiomerically pure compounds.
![(S)-(+)-2-[2-(Diphenylphosphino)phenyl]-4-phenyl-2-oxazoline (C27H22NOP) — chemical structure, CAS 148461-15-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F148461-15-8.png&w=3840&q=75)
Chiral Ligand in Asymmetric Catalysis
This oxazoline-based phosphine ligand is extensively used in transition metal catalysis to achieve high enantioselectivity in various organic reactions, such as hydrogenations, allylic alkylations, and cyclopropanations.
Synthesis of Enantiomerically Pure Compounds
It serves as a crucial building block or catalyst component in the stereoselective synthesis of complex chiral molecules, including pharmaceutical intermediates and fine chemicals.
Research and Development
Researchers utilise this ligand to explore new catalytic methodologies and develop novel asymmetric transformations, contributing to advancements in synthetic organic chemistry.
| Molecular weight | 407.44 |
|---|---|
| Empirical formula | C27H22NOP |
| Assay | ≥97.0% (31P-NMR) |
| Optical activity | [α]20/D +29.5±3°, c = 1% in chloroform |
| Melting point | 89-93 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-[2-(Diphenylphosphino)phenyl]-4-phenyl-2-oxazoline used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis to promote stereoselective synthesis of enantiomerically pure compounds.
What are the CAS number and formula for this chemical?
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The CAS number is 148461-15-8, and the molecular formula is C27H22NOP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥97.0% (31P-NMR). We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should (S)-(+)-2-[2-(Diphenylphosphino)phenyl]-4-phenyl-2-oxazoline be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Ensure adequate ventilation.
Is this compound a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How is this product packed, shipped, and exported?
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Tech Serve Solutions packs and ships chemicals professionally, adhering to all necessary regulations for domestic and international export.
How can I request a sample or a quote?
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Please contact our sales team via the website or direct inquiry to request a sample or obtain a quote for this product.
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