(R,S)-AM1241
(R,S)-AM1241 (CAS: 444912-48-5), with the molecular formula C22H22IN3O3 and a molecular weight of 503.33, is a selective CB2 cannabinoid receptor agonist. This iodinated derivative is primarily used in preclinical research to investigate neuropathic pain mechanisms in animal models. Its role as a pharmacological tool makes it valuable for neurobiology and pain research.
- IUPAC
- (R,S)-3-(2-Iodo-5-nitrobenzoyl)-1-(1-methyl-2-piperidinylmethyl)-1H-indole
- Synonyms
- (R,S)-3-(2-Iodo-5-nitrobenzoyl)-1-(1-methyl-2-piperidinylmethyl)-1H-indole
Neuropathic Pain Research
(R,S)-AM1241 serves as a selective CB2 cannabinoid receptor agonist. It has been employed in studies to explore the aetiology and potential therapeutic targets for neuropathic pain in various animal models.
Cannabinoid Receptor Studies
This compound is utilised as a research tool to investigate the specific roles and functions of CB2 cannabinoid receptors within biological systems. Its selectivity aids in delineating the pharmacological effects mediated by these receptors.
Neuropharmacological Research
As a tool in neurobiology and neuropharmacology, (R,S)-AM1241 assists researchers in understanding the complex pathways involved in pain signalling and other neurological processes influenced by the endocannabinoid system.
| Molecular weight | 503.33 |
|---|---|
| Empirical formula | C22H22IN3O3 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | yellow |
| Solubility | DMSO: ~18 mg/mL at 60 °C |
| Application | (R,S)-AM1241, a selective CB2 cannabinoid receptor agonist, has been used to study neuropathic pain in animal models. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 22-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | regulated under CDSA - not available from Canada |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R,S)-AM1241 used for?
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(R,S)-AM1241 is a selective CB2 cannabinoid receptor agonist used in preclinical research, particularly for studying neuropathic pain in animal models and for investigating cannabinoid receptor functions.
What is the CAS number and molecular formula for (R,S)-AM1241?
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The CAS number is 444912-48-5 and the molecular formula is C22H22IN3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R,S)-AM1241 with an assay of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should (R,S)-AM1241 be handled safely?
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Due to potential irritation and sensitisation hazards (H315, H319, H334, H335), handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, faceshields, and gloves. Ensure good ventilation. Refer to the Safety Data Sheet for full details.
Is (R,S)-AM1241 a controlled substance?
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(R,S)-AM1241 is regulated under the Controlled Drugs and Substances Act (CDSA) in Canada and is not available from Tech Serve Solutions in Canada.
How can I request a sample or quote for (R,S)-AM1241?
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To request a sample or obtain a quotation, please contact our sales department via the website or direct email, providing your research requirements.
How is (R,S)-AM1241 supplied and exported?
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(R,S)-AM1241 is supplied as a yellow solid. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
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