(R,R,R)-1-(3,5-Dioxa-4-phosphacyclohepta[2,1-a:3,4-a′]dinaphthalen-4-yl)-2,5-diphenylpyrrolidine
(R,R,R)-1-(3,5-Dioxa-4-phosphacyclohepta[2,1-a:3,4-a′]dinaphthalen-4-yl)-2,5-diphenylpyrrolidine (CAS 444667-33-8) is a chiral phosphine ligand with the empirical formula C36H28NO2P and a molecular weight of 537.59. This organophosphorus compound is primarily utilised in asymmetric synthesis, serving as a valuable tool for enantioselective transformations in chemical synthesis and catalysis.
- IUPAC
- 1-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-(2R,5R)-2,5-diphenylpyrrolidine
- Synonyms
- 444667-33-8(R,R,R)-1-(3,5-Dioxa-4-phosphacyclohepta[2,1-a:3,4-a′]dinaphthalen-4-yl)-2,5-diphenylpyrrolidine1-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-(2R,5R)-2,5-diphenylpyrrolidine
![(R,R,R)-1-(3,5-Dioxa-4-phosphacyclohepta[2,1-a:3,4-a′]dinaphthalen-4-yl)-2,5-diphenylpyrrolidine (R)-1-(3) — chemical structure, CAS 444667-33-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F444667-33-8.png&w=3840&q=75)
Asymmetric Hydrogenation
This compound functions as a chiral ligand in asymmetric hydrogenation reactions, enabling the enantioselective reduction of prochiral substrates. Its specific structure facilitates high levels of stereocontrol in catalytic processes.
Chiral Catalyst Development
As a privileged ligand, it is instrumental in the development of novel chiral catalysts for a variety of asymmetric transformations. Its phosphoramidite nature offers unique coordination properties with transition metals.
Fine Chemical Synthesis
Its application extends to the synthesis of complex organic molecules and pharmaceutical intermediates where precise stereochemical control is paramount. It is a key reagent in advanced chemical synthesis.
| Molecular weight | 537.59 |
|---|---|
| Empirical formula | C36H28NO2P |
| Assay | 90% |
| Optical activity | [α]22/D −237°, c = 0.5 in chloroform |
| Storage temperature | −20°C |
| Application | Used in asymmetric hydrogenation. |
| Melting point | 191-196 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R,R,R)-1-(3,5-Dioxa-4-phosphacyclohepta[2,1-a:3,4-a′]dinaphthalen-4-yl)-2,5-diphenylpyrrolidine used for?
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This compound is used in asymmetric hydrogenation and as a chiral catalyst ligand in various asymmetric synthesis applications.
What are the CAS number and empirical formula?
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The CAS number is 444667-33-8, and the empirical formula is C36H28NO2P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 90%. It is not presented as USP, EP, BP, or any pharmacopoeial grade.
How should this chemical be handled and stored?
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This chemical has a GHS hazard classification of 3 for water hazard in Germany. It should be stored at -20°C. Always consult the Safety Data Sheet (SDS) for detailed handling and safety precautions.
How is this product packed and shipped?
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This product is carefully packed and exported by Tech Serve Solutions, adhering to all necessary regulations for chemical transport.
How can I request a sample or quote for this chemical?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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