R(+)-Methanandamide
R(+)-Methanandamide (CAS: 157182-49-5), with the molecular formula C23H39NO2 and a molecular weight of 361.56 g/mol, is a bioactive small molecule and cannabinoid. It is primarily utilised in research settings, particularly within cell biology, cell signaling, neuroscience, and neurobiology. Its optical activity is documented as [α]/D +8.7°, c = 4 in chloroform.
- IUPAC
- AM-356,R(+)-Arachidonyl-1′-hydroxy-2′-propylamide

Neuroscience Research
R(+)-Methanandamide serves as a valuable tool in neuroscience research, aiding investigations into cannabinoid receptors and signaling pathways within the central nervous system. Its specific interactions contribute to understanding neurotransmission and neurobiological processes.
Cell Signaling Studies
This compound is employed in studies of cell signaling, offering insights into the complex mechanisms that regulate cellular communication. Researchers utilise it to explore the effects of endocannabinoid system modulation on various cellular functions.
Bioactive Molecule Investigations
As a bioactive small molecule, R(+)-Methanandamide is instrumental in exploring biological activities and potential pharmacological applications. Its defined chemical structure and properties make it suitable for screening and mechanism-of-action studies.
| Molecular weight | 361.56 |
|---|---|
| Empirical formula | C23H39NO2 |
| Assay | ≥96% (HPLC) |
| Concentration | 5 mg/mL in absolute ethanol |
| Optical activity | [α]/D +8.7°, c = 4 in chloroform(lit.) |
| Storage temperature | −20°C |

Hazard statements
- H225Highly flammable liquid and vapour
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 14 °C / 57.2 °F |
| Transport (UN / ADR) | UN 1170C 3 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11 |
| Safety statements (S) | 7-16 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | regulated under CDSA - not available from Canada |
|---|---|
| Gene Information | mouse ... Cnr1(12801), Cnr2(12802)rat ... Cnr1(25248) |
| Storage Condition | desiccatedprotect from lightunder inert gas |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is R(+)-Methanandamide used for?
+
R(+)-Methanandamide is primarily used in research settings, including neuroscience, cell biology, and cell signaling studies, to investigate cannabinoid pathways and biological activities.
What are the CAS number and formula for R(+)-Methanandamide?
+
The CAS number for R(+)-Methanandamide is 157182-49-5 and its molecular formula is C23H39NO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies R(+)-Methanandamide with a purity of ≥96% by HPLC. We do not represent this product as USP, BP, or EP grade.
How should R(+)-Methanandamide be handled and stored?
+
R(+)-Methanandamide is flammable (H225) and requires careful handling. Store it at −20°C, desiccated, protected from light, and under an inert gas. Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Refer to the safety data sheet for comprehensive guidance.
Is R(+)-Methanandamide a controlled substance?
+
Yes, R(+)-Methanandamide is regulated under CDSA and is not available from Canada due to its controlled status.
How can I request a quote or sample for R(+)-Methanandamide?
+
To request a quote or sample of R(+)-Methanandamide, please contact our sales department through the website or by phone.
How is R(+)-Methanandamide packaged and shipped?
+
R(+)-Methanandamide is typically packaged according to international shipping regulations for hazardous materials and is exported globally by Tech Serve Solutions. Specific packaging details are available upon request.
▶ Related products

(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology

(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis