R-(+)-DIOA
R-(+)-DIOA (CAS 81166-47-4) is a white, solid chemical compound with the molecular formula C20H24Cl2O4 and a molecular weight of 399.31 g/mol. This molecule functions as a modulator of voltage-gated chloride channels. It is primarily utilised in research settings for its specific interactions with ion channels, contributing to studies in cell biology and neuroscience, particularly in understanding cell signalling pathways.
- IUPAC
- R(+)-Butylindazone,R-(+)-[(2-n-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]acetic acid
- Synonyms
- R(+)-ButylindazoneR-(+)-[(2-n-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]acetic acid
Chloride Channel Modulation
R-(+)-DIOA is employed as a modulator for voltage-gated chloride channels. Its activity aids in researching the function and regulation of these crucial ion channels in various biological systems.
Cell Signaling Research
This compound is valuable in studies investigating cell signalling pathways. By interacting with specific ion channels, it provides insights into the complex mechanisms that govern cellular communication and responses.
Neuroscience Investigations
R-(+)-DIOA is utilised in neuroscience research to explore the role of chloride channels in neuronal function. Its application helps in understanding the electrophysiology of nerve cells and related disorders.
Bioactive Small Molecule Studies
As a bioactive small molecule, R-(+)-DIOA is used in biochemical and pharmacological research. It serves as a tool to probe biological processes at the molecular level.
| Molecular weight | 399.31 |
|---|---|
| Empirical formula | C20H24Cl2O4 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | H2O: insoluble DMSO: >20 mg/mL0.1 M HCl: insoluble0.1 M NaOH: solubleethanol: soluble |
| Optical activity | [α]27/D +18.1°, c = 0.7 in methanol(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is R-(+)-DIOA used for?
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R-(+)-DIOA is used in research for modulating voltage-gated chloride channels, investigating cell signalling, and in neuroscience studies.
What are the CAS number and chemical formula for R-(+)-DIOA?
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The CAS number for R-(+)-DIOA is 81166-47-4, and its chemical formula is C20H24Cl2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies R-(+)-DIOA with a purity of ≥98% (HPLC). This product is intended for research and laboratory use. TSS does not represent it as USP, BP, or EP grade.
How should R-(+)-DIOA be handled safely?
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When handling R-(+)-DIOA, it is essential to wear appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, due to its potential hazards. Refer to the safety data sheet for comprehensive information.
Is R-(+)-DIOA a controlled substance?
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The provided data does not indicate that R-(+)-DIOA is a controlled substance.
How is R-(+)-DIOA packed and shipped?
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R-(+)-DIOA is supplied as a white solid. Specific packing and shipping details are available upon request to ensure safe and compliant transport.
How can I request a sample or quote for R-(+)-DIOA?
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To request a sample or a quote for R-(+)-DIOA, please contact our sales department through the website or direct email, specifying the CAS number 81166-47-4.
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