(R)-Boc-5-oxopyrrolidine-2-carboxylic acid
(R)-Boc-5-oxopyrrolidine-2-carboxylic acid (CAS: 160347-90-0, C10H15NO5) is a chiral building block with a molecular weight of 229.23 g/mol. This pyroglutamic acid derivative is valuable in asymmetric synthesis and chemical biology. Its protected carboxyl group and chiral center make it a key intermediate in the construction of complex molecules, particularly in peptide chemistry and the development of unnatural amino acid derivatives. It is supplied with an assay of 97% and requires storage at 2-8°C.
- IUPAC
- (+)-1-Boc-D-pyroglutamic acid,Boc-D-pyr-OH
- Synonyms
- (+)-1-Boc-D-pyroglutamic acidBoc-D-pyr-OH
Chiral Synthesis
This compound serves as a crucial chiral building block in asymmetric synthesis. Its defined stereochemistry allows for the stereoselective construction of complex organic molecules.
Peptide Chemistry
As an unnatural amino acid derivative, it is employed in peptide synthesis to introduce modified structural elements. This enables the development of peptides with altered stability, conformation, or biological activity.
Chemical Biology Research
It finds application in chemical biology for creating novel probes or modified biomolecules. Its structure is useful for investigating biological pathways and interactions.
Heterocyclic Compound Synthesis
The pyrrolidine ring system within this molecule makes it a valuable precursor for synthesising various heterocyclic compounds, which are prevalent in pharmaceuticals.
| Molecular weight | 229.23 |
|---|---|
| Empirical formula | C10H15NO5 |
| Assay | 97% |
| Optical activity | [α]22/D +35°, c = 1 in chloroform |
| Storage temperature | 2-8°C |
| Melting point | 111-116 °C (dec.) |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Boc-5-oxopyrrolidine-2-carboxylic acid used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis, peptide chemistry, chemical biology research, and the synthesis of heterocyclic compounds.
What are the CAS number and formula for (R)-Boc-5-oxopyrrolidine-2-carboxylic acid?
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The CAS number is 160347-90-0 and the empirical formula is C10H15NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Boc-5-oxopyrrolidine-2-carboxylic acid with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound is a Warning hazard (H319), causing serious eye irritation. Wear eyeshields, gloves, and a dust mask type N95 (US). In case of contact with eyes, rinse cautiously with water for several minutes; remove contact lenses, if present and easy to do. Continue rinsing. It is also designated WGK 3 in Germany, indicating high water hazard.
How is this chemical typically packed and exported?
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This chemical is carefully packed according to international shipping regulations and exported globally by TSS.
How can I request a sample or quote for this product?
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Please contact our sales team via the website or by phone to request a sample or a detailed quotation.
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