(R)-(−)-8a-Methyl-3,4,8,8a-tetrahydro-1,6(2H,7H)-naphthalenedione
(R)-(−)-8a-Methyl-3,4,8,8a-tetrahydro-1,6(2H,7H)-naphthalenedione (CAS: 100348-93-4) is a chiral organic compound with the molecular formula C11H14O2 and a molecular weight of 178.23 g/mol. This dione is valuable in asymmetric synthesis and organic chemical synthesis as a chiral building block. Its specific stereochemistry makes it a useful precursor in the creation of complex molecules, particularly where enantiomeric purity is critical.
- IUPAC
- (R)-(−)-9-Methyl-5(10)-octaline-1,6-dione,(R)-Miescher-Wieland ketone
- Synonyms
- 8a-tetrahydro-1,6(2H,7H)-naphthalenedione(R)-Miescher-Wieland ketone

Chiral Building Block
Serves as a crucial chiral synthon in the stereoselective synthesis of complex organic molecules. Its defined stereochemistry allows for the precise construction of enantiomerically enriched target compounds.
Asymmetric Synthesis
Employed in various asymmetric synthesis strategies to introduce chirality and control stereochemical outcomes in reactions. It is a valuable reagent for chemists focused on enantioselective transformations.
Organic Synthesis
A versatile intermediate in general organic synthesis, enabling the construction of polycyclic structures and molecules with specific stereochemical requirements. Useful in research and development settings.
| Molecular weight | 178.23 |
|---|---|
| Empirical formula | C11H14O2 |
| Assay | ≥98.0% (sum of enantiomers, GC) |
| Optical activity | [α]20/D −98±2°, c = 1.1% in benzene |
| Storage temperature | 2-8°C |
| Melting point | 49-51 °C |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-8a-Methyl-3,4,8,8a-tetrahydro-1,6(2H,7H)-naphthalenedione used for?
+
(R)-(−)-8a-Methyl-3,4,8,8a-tetrahydro-1,6(2H,7H)-naphthalenedione is primarily used as a chiral building block in asymmetric synthesis and general organic synthesis for the creation of complex stereochemically defined molecules.
What are the CAS number and molecular formula?
+
The CAS number is 100348-93-4, and the molecular formula is C11H14O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound with an assay of ≥98.0% (sum of enantiomers, GC). This is a research grade material and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling recommendations?
+
Recommended personal protective equipment includes eyeshields and gloves. European safety statements are 22-24/25, and it has a WGK Germany rating of 3. Store at 2-8°C.
How is this chemical shipped and exported by TSS?
+
Tech Serve Solutions, a specialist global supplier and exporter since 1998, professionally packages and exports chemicals worldwide in compliance with international shipping regulations.
How can I request a sample or quote for this chemical?
+
To request a sample or a quotation, please contact the TSS sales team through our website or by phone, providing the product name and CAS number (100348-93-4).
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis