(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol

CAS 127852-28-2C10H8F6OChemical Synthesis

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol (CAS: 127852-28-2) is a chiral alcohol with the molecular formula C10H8F6O and a molecular weight of 258.16 g/mol. This compound serves as a valuable building block in asymmetric synthesis and organic chemistry. Its specific stereochemistry makes it particularly useful for creating enantiomerically pure compounds, finding applications in the development of novel pharmaceuticals and advanced materials. It is supplied by TSS with an assay of ≥98.0% (GC).

Synonyms: C10H8F6O

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(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol (C10H8F6O) — chemical structure, CAS 127852-28-2; Chemistry, fine chemical supplied by Tech Serve Solutions

AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks

01 /Applications

Chiral Building Block

Utilised in asymmetric synthesis to construct enantiomerically pure molecules. Its defined stereocenter is crucial for developing chirally specific intermediates and final products.

Pharmaceutical Intermediate

Serves as a key intermediate in the synthesis of complex pharmaceutical compounds. Its fluorinated structure can impart unique properties to drug candidates.

Organic Synthesis Reagent

Employed in various organic transformations requiring a chiral alcohol moiety. Its reactivity allows for diverse derivatisation and further synthetic elaboration.

Material Science Research

Explored in the development of advanced materials where specific stereochemical properties are required. The bis(trifluoromethyl)phenyl group can influence material characteristics.

02 /Properties

Molecular weight	258.16
Empirical formula	C10H8F6O
Assay	≥98.0% (GC)
Optical activity	[α]/D +27±1°, c = 1 in acetonitrile
Optical purity	enantiomeric ratio: 97:3 (GC)
Melting point	53-58 °C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-52/53
Safety statements (S)	61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

127852-28-2

MDL number

MFCD03093010

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol used for?

This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in organic and pharmaceutical synthesis. Its specific stereochemistry is valuable for creating enantiomerically pure compounds.

What is the CAS number and molecular formula for this compound?

The CAS number is 127852-28-2 and the molecular formula is C10H8F6O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol with an assay of ≥98.0% (GC). This is considered a technical or research grade, and TSS does not represent it as USP, BP, or EP grade.

How should (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol be handled?

This compound is classified as harmful if swallowed (H302). When handling, it is recommended to use a dust mask type N95 (US), wear eyeshields, and use gloves. Ensure good ventilation and avoid ingestion and contact with skin and eyes.

Is this chemical packed and shipped internationally?

Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this product, and can arrange for international packing and shipping.

How can I request a sample or quote for this chemical?

To request a sample or a quote for (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol, please use the contact form on our website or contact our sales department directly.