Pyrrolidine
Pyrrolidine (CAS: 123-75-1), with the chemical formula C4H9N and a molecular weight of 71.12 g/mol, is a saturated heterocyclic amine. It is a clear, colourless liquid known for its amine odour. Pyrrolidine serves as a fundamental building block in organic synthesis, particularly for creating more complex heterocyclic compounds and pharmaceutical intermediates. Its reactive nature makes it a valuable reagent in various chemical transformations.
- IUPAC
- Tetrahydropyrrole,Tetramethyleneimine
- Synonyms
- TetrahydropyrroleTetramethyleneimine
Organic Synthesis Reagent
Pyrrolidine is widely used as a key intermediate and building block in the synthesis of diverse organic molecules. It is instrumental in the formation of more complex heterocyclic structures.
Pharmaceutical Intermediates
This compound is a crucial starting material for the production of various active pharmaceutical ingredients (APIs) and drug candidates. Its pyrrolidine ring is a common motif in many medicinal compounds.
Agrochemical Development
Pyrrolidine derivatives are explored and utilised in the development of novel agrochemicals, contributing to the synthesis of pesticides and herbicides.
Specialty Chemicals
It finds application in the synthesis of specialty chemicals, dyes, and polymers where its unique structure imparts desired properties.
| Molecular weight | 71.12 |
|---|---|
| Empirical formula | C4H9N |
| Assay | ≥99.5% |
| Boiling point | 87-88 °C/760 mmHg(lit.) |
| Density | 0.852 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.443(lit.) |
| Vapour pressure | 128 mmHg (39 °C)49 mmHg (20 °C) |
| Vapour density | 2.45 (vs air) |
| Autoignition temp | 653 °F |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 3 °C / 37.4 °F |
| Transport (UN / ADR) | UN 1922 8(3) / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-20/22-35 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Purified By | redistillation |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pyrrolidine used for?
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Pyrrolidine is primarily used as a building block in organic synthesis, particularly for creating pharmaceutical intermediates and other complex heterocyclic compounds.
What are the CAS number and chemical formula for Pyrrolidine?
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The CAS number for Pyrrolidine is 123-75-1, and its chemical formula is C4H9N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pyrrolidine with an assay of ≥99.5%. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should Pyrrolidine be handled safely?
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Pyrrolidine is a flammable liquid and causes severe skin burns and eye damage (H225, H314). Handling requires appropriate personal protective equipment, including chemical-resistant gloves, safety goggles, and a face shield. Work should be conducted in a well-ventilated area or fume hood, away from ignition sources.
How is Pyrrolidine shipped and exported?
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Pyrrolidine is shipped as a UN 1922, Hazard Class 8 (3), Packing Group II. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant transportation regulations.
How can I request a sample or quote for Pyrrolidine?
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To request a sample or a quotation for Pyrrolidine, please contact our sales team through the website or by phone, providing your specific requirements.
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