PTH-histidine
3-Phenyl-2-thiohydantoin of Histidine (PTH-Histidine), CAS 5835-68-7, has the molecular formula C13H12N4OS and a molecular weight of 272.33 g/mol. This compound is a key derivative used in protein sequencing, particularly for identifying histidine residues. Its application in structural analysis and proteomics makes it a valuable reagent for researchers investigating protein function and modification. Stored at −20°C, PTH-Histidine is supplied by TSS for research purposes.

Protein Sequencing
PTH-Histidine is employed in the Edman degradation process to identify histidine residues within a peptide chain. It serves as a standard for comparison during chromatographic analysis of the released phenylthiohydantoin derivatives.
Protein Structural Analysis
As a derivative of histidine, this compound aids in studies focused on protein structure and the role of specific amino acids in maintaining that structure. It is instrumental in mapping the sequence of proteins.
Proteomics Research
In the broader field of proteomics, PTH-Histidine is used for precise identification and quantification of proteins and their modifications. It supports advanced research into cellular mechanisms and disease.
Reagent for Biochemical Assays
This compound functions as a specialised reagent in various biochemical assays, particularly those involving amino acid analysis and characterisation of protein components.
| Molecular weight | 272.33 |
|---|---|
| Empirical formula | C13H12N4OS |
| Storage temperature | −20°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PTH-Histidine primarily used for?
+
PTH-Histidine is primarily used in protein sequencing, specifically for the identification of histidine residues using methods like Edman degradation and for protein structural analysis and proteomics research.
What are the CAS number and formula for PTH-Histidine?
+
The CAS number for PTH-Histidine is 5835-68-7, and its empirical formula is C13H12N4OS.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies PTH-Histidine for research use. The specific assay is not detailed; therefore, TSS does not represent it as USP, BP, or EP grade.
How should PTH-Histidine be handled and stored?
+
PTH-Histidine should be handled with appropriate laboratory precautions. The product data indicates storage at −20°C. Refer to the Safety Data Sheet for detailed handling procedures.
Is PTH-Histidine a controlled substance?
+
The provided data does not indicate that PTH-Histidine is a controlled substance.
How are Tech Serve Solutions products shipped and exported?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, laboratory reagents, and pharmaceutical intermediates, adhering to all relevant shipping and export regulations.
How can I request a sample or quote for PTH-Histidine?
+
To request a sample or a quote for PTH-Histidine, please contact our sales department through the website or via direct inquiry.
▶ Related products

Acrylamide
Molecular Biology

Agarose
Molecular Biology

N,N′-Methylenebisacrylamide
Molecular Biology

Zinc sulfate solution
Molecular Biology

(±)-Jasmonic acid
C12H18O3
Molecular Biology
(−)-cis,trans-Abscisic acid
Molecular Biology

(2,4-Dichlorophenoxy)acetic acid sodium salt monohydrate
Molecular Biology

(2R,5R)-Bis(hydroxymethyl)-(3R,4R)-dihydroxypyrrolidine
Molecular Biology
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis