Proguanil hydrochloride
Proguanil hydrochloride (CAS 637-32-1), with the molecular formula C11H16ClN5·HCl and a molecular weight of 290.19, is a chemical compound utilised in the development of antimalarial drugs. It functions as an anti-parasitic protozoan agent. Research applications focus on studying its pharmacokinetics, metabolism, safety, and efficacy. This compound is supplied by Tech Serve Solutions as a solid for research and development purposes.
- IUPAC
- Chlorguanide,N1-(4-Chlorophenyl)-N5-isopropylbiguanide
- Synonyms
- Chlorguanide,N1-(4-Chlorophenyl)-N5-isopropylbiguanide
Antimalarial Drug Development
Proguanil hydrochloride serves as a key compound in research for new antimalarial therapeutics. Its role involves investigating methods to combat parasitic protozoa responsible for malaria.
Pharmacokinetic and Metabolic Studies
This compound is used to study the absorption, distribution, metabolism, and excretion (ADME) properties of potential antimalarial drugs. Understanding these parameters is crucial for drug design and safety profiling.
Safety and Efficacy Research
Researchers utilise proguanil hydrochloride to assess the safety profile and therapeutic efficacy of antimalarial drug candidates. This helps in determining dosage and potential side effects.
| Molecular weight | 290.19 |
|---|---|
| Empirical formula | C11H16ClN5·HCl |
| Assay | ≥95% (HPLC) |
| Form | solid |
| Solubility | acetonitrile: water: ~1 mg/mL (60/40) |
| Storage temperature | 2-8°C |
| Application | Proguanil (chlorguanide) may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug. |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Proguanil hydrochloride used for?
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Proguanil hydrochloride (CAS 637-32-1) is used in anti-parasitic protozoan drug development, particularly for antimalarial research, to study its pharmacokinetics, metabolism, safety, and efficacy.
What are the CAS number and formula for Proguanil hydrochloride?
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The CAS number for Proguanil hydrochloride is 637-32-1, and its empirical formula is C11H16ClN5·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Proguanil hydrochloride with an assay of ≥95% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product data.
What are the safety considerations for Proguanil hydrochloride?
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Proguanil hydrochloride is classified with GHS06 symbol and 'Danger' signal word, indicating toxicity. Hazard statements include H301 (Toxic if swallowed). Precautionary statements include P301 + P310 (IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician). Handle with extreme care, wearing appropriate personal protective equipment.
How is Proguanil hydrochloride shipped and exported?
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Proguanil hydrochloride is shipped and exported in compliance with international regulations for hazardous materials. It is classified under UN 2811, Hazard Class 6.1, Packing Group III.
How can I request a sample or quote for Proguanil hydrochloride?
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To request a sample or a quote for Proguanil hydrochloride, please contact our sales department through the website or via direct inquiry, providing your specific requirements and shipping details.
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