Potassium cyclopropyltrifluoroborate
Potassium cyclopropyltrifluoroborate (CAS: 1065010-87-8), with the molecular formula C3H5BF3K and a molecular weight of 147.98 g/mol, is a valuable organotrifluoroborate reagent. It serves as a stable and versatile surrogate for boronic acids in synthetic organic chemistry. This compound is particularly noted for its utility in palladium-catalysed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the efficient formation of carbon-carbon bonds in complex molecule synthesis.
Suzuki-Miyaura Cross-Coupling Reactions
Potassium cyclopropyltrifluoroborate is extensively employed as a coupling partner in Suzuki-Miyaura reactions. This palladium-catalysed process allows for the efficient formation of C-C bonds, making it indispensable for the synthesis of biaryl compounds and other complex organic structures.
Synthesis of Complex Organic Molecules
Its role as a stable boronic acid surrogate makes it a preferred reagent in multi-step syntheses. The trifluoroborate moiety offers improved stability and handling compared to traditional boronic acids, facilitating its integration into various synthetic strategies.
Research and Development in Medicinal Chemistry
The ability to readily introduce the cyclopropyl group via cross-coupling makes this reagent useful in drug discovery programmes. It enables medicinal chemists to explore structure-activity relationships by incorporating this motif into potential therapeutic candidates.
| Molecular weight | 147.98 |
|---|---|
| Empirical formula | C3H5BF3K |
| Application | Organotrifluoroborate involved in Suzuki-Miyaura cross-coupling reactions1,2,3,4,5,6Organotrifluoroborates as versatile and stable boronic acid surrogates. |
| Melting point | 348-350 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium cyclopropyltrifluoroborate used for?
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Potassium cyclopropyltrifluoroborate is used as a reagent in Suzuki-Miyaura cross-coupling reactions and for the synthesis of complex organic molecules. It acts as a stable surrogate for boronic acids.
What are the CAS number and formula for Potassium cyclopropyltrifluoroborate?
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The CAS number is 1065010-87-8 and the empirical formula (Hill notation) is C3H5BF3K.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Potassium cyclopropyltrifluoroborate as a research-grade chemical. We do not represent it as meeting USP, BP, or EP pharmacopoeia standards.
How should Potassium cyclopropyltrifluoroborate be handled safely?
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Potassium cyclopropyltrifluoroborate is classified as hazardous. It is harmful if swallowed, causes skin irritation, and causes serious eye irritation. Always handle with appropriate personal protective equipment in a well-ventilated area.
How is Potassium cyclopropyltrifluoroborate packed and exported?
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Potassium cyclopropyltrifluoroborate is carefully packed to ensure product integrity during transit. Tech Serve Solutions is experienced in exporting fine chemicals globally.
How can I request a sample or quote for Potassium cyclopropyltrifluoroborate?
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To request a sample or a quote, please contact our sales team through the website or by email, providing your specific requirements.
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