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Potassium 4-formylphenyltrifluoroborate

CAS 374564-36-0CHOC6H4BF3KChemical Synthesis

Potassium 4-formylphenyltrifluoroborate (CAS 374564-36-0) is a white to off-white solid with the linear formula CHOC6H4BF3K and a molecular weight of 212.02 g/mol. This organoboron compound serves as a versatile building block in organic synthesis. It is commonly employed in Suzuki-Miyaura cross-coupling reactions and other transition-metal catalysed transformations for the introduction of the 4-formylphenyl moiety into complex molecules, finding utility in pharmaceutical and materials science research.

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Potassium 4-formylphenyltrifluoroborate (CHOC6H4BF3K) — chemical structure, CAS 374564-36-0; Chemistry, fine chemical supplied by Tech Serve Solutions
AldehydesAryl Trifluoroborate SaltsBuilding BlocksCarbonyl CompoundsChemical SynthesisOrganic Building BlocksOrganometallic Reagents
01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

Potassium 4-formylphenyltrifluoroborate is an effective coupling partner in palladium-catalysed Suzuki-Miyaura reactions. It allows for the efficient formation of carbon-carbon bonds, introducing an aldehyde-functionalized phenyl ring into various organic scaffolds.

Organic Synthesis Building Block

As a functionalized aryl trifluoroborate, this compound is valuable for constructing more complex organic molecules. The presence of both the trifluoroborate group and the aldehyde functionality offers multiple synthetic handles for further elaboration.

Pharmaceutical Intermediate Research

The introduction of formylphenyl groups can be a key step in the synthesis of novel pharmaceutical candidates. This reagent facilitates research into new drug discovery and development programmes.

Materials Science Applications

Functionalised aromatic compounds are integral to the development of advanced materials. Potassium 4-formylphenyltrifluoroborate can be used in the synthesis of organic electronic materials or polymers with tailored properties.

02 /Properties
Molecular weight212.02
Linear formulaCHOC6H4BF3K
Melting point>300 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
374564-36-0
MDL number
MFCD02093980
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Potassium 4-formylphenyltrifluoroborate used for?

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Potassium 4-formylphenyltrifluoroborate is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions. It is employed in research for creating complex molecules, including potential pharmaceutical intermediates and materials science components.

What are the CAS number and formula for Potassium 4-formylphenyltrifluoroborate?

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The CAS number is 374564-36-0 and the linear formula is CHOC6H4BF3K.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this compound as a research-grade chemical. The exact purity is available on the Certificate of Analysis (CoA). We do not represent this product as USP, BP, EP, or pharmaceutical grade.

What are the safety and handling precautions for Potassium 4-formylphenyltrifluoroborate?

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This compound is classified as a Warning irritant, with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.

How is Potassium 4-formylphenyltrifluoroborate packaged and shipped?

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This chemical is carefully packaged to ensure safe transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.

How can I request a quote or sample?

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To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (374564-36-0).

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