Pioglitazone hydrochloride
Pioglitazone hydrochloride (CAS: 112529-15-4), with the empirical formula C19H20N2O3S · HCl and a molecular weight of 392.90, is a white to off-white powder. This compound is primarily recognised for its role as an approved therapeutic agent and is utilized in research settings as a bioactive small molecule. Its applications span cell biology, cell signaling, and neuroscience, with a specific focus on gene regulation and expression, particularly concerning PPAR and RXR pathways.
- IUPAC
- 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride
Research in Metabolic Disorders
Pioglitazone hydrochloride serves as a valuable tool for researchers investigating metabolic pathways, particularly those involving insulin resistance and type 2 diabetes. Its mechanism of action as a PPARγ agonist makes it instrumental in studying cellular responses and signaling.
Cell Signaling and Neuroscience Studies
The compound is employed in research focused on cell signaling pathways, including those relevant to neuroscience. Investigations into gene regulation and expression modulated by PPAR and RXR receptors often utilise pioglitazone hydrochloride.
Bioactive Small Molecule Research
As a bioactive small molecule, pioglitazone hydrochloride is used in various cell biology applications to probe cellular functions and responses. Its well-defined biological activity aids in understanding complex biological systems.
| Molecular weight | 392.90 |
|---|---|
| Empirical formula | C19H20N2O3S · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | DMSO: ≥10 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pioglitazone hydrochloride used for?
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Pioglitazone hydrochloride is used as an approved therapeutic agent, primarily in research related to metabolic disorders, cell signaling, neuroscience, and gene regulation. It acts as a PPARγ agonist.
What is the CAS number and formula for Pioglitazone hydrochloride?
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The CAS number for Pioglitazone hydrochloride is 112529-15-4, and its empirical formula is C19H20N2O3S · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pioglitazone hydrochloride with a purity of ≥98% (HPLC). This product is supplied for research and laboratory use and is not represented as USP, BP, or EP grade.
What are the safety and handling considerations for Pioglitazone hydrochloride?
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Pioglitazone hydrochloride is classified with a GHS07 symbol and a 'Warning' signal word, indicating it causes serious eye irritation (H319). Handle with appropriate personal protective equipment, including eye protection, and follow P305 + P351 + P338 procedures if contact occurs.
How is Pioglitazone hydrochloride supplied and shipped?
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Pioglitazone hydrochloride is supplied as a white to off-white powder and is typically stored at room temperature. TSS exports chemicals globally, adhering to all relevant shipping and handling regulations.
How can I request a sample or quote for Pioglitazone hydrochloride?
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To request a sample or a quotation for Pioglitazone hydrochloride, please contact our sales team through the website or by phone, providing your specific requirements.
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