Pinacidil monohydrate
Pinacidil monohydrate (CAS: 85371-64-8; C13H19N5 · H2O) is a white to beige powder with a molecular weight of 263.34 g/mol. As a potent activator of ATP-sensitive potassium channels, it is widely utilized in scientific research. Its applications span cell biology, ion channel studies, and cell signaling research, making it a valuable reagent for understanding cellular electrophysiology and related physiological processes.
- IUPAC
- (±)-N-Cyano-N′-4-pyridinyl-N″-(1,2,2-trimethylpropyl)guanidine monohydrate
Potassium Channel Modulation Research
Pinacidil monohydrate serves as a critical tool for researchers investigating the function and regulation of ATP-sensitive potassium (KATP) channels. It is used to probe channel activity in various cell types and tissues.
Cellular Electrophysiology Studies
This compound is employed in electrophysiology experiments to study the effects of KATP channel activation on cell membrane potential and ion flux. Its specific action aids in understanding cellular excitability.
Cell Signaling and Neuroscience
Researchers utilise Pinacidil monohydrate to explore its role in cell signaling pathways and its potential impact on neuronal function, particularly concerning ion channel-mediated processes in the nervous system.
Pharmacological Research Tool
As a well-characterised bioactive small molecule, Pinacidil monohydrate is valuable for in vitro pharmacological studies and as a reference compound in drug discovery programs focused on ion channel targets.
| Molecular weight | 263.34 |
|---|---|
| Empirical formula | C13H19N5 · H2O |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble15 mg/mL, clear45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble40 mg/mL |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | mouse ... Kcnj11(16514)rat ... Kcna1(24520), Kcnj1(24521), Kcnj11(83535), Kcnj5(29713), Kcnj8(25472) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pinacidil monohydrate used for?
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Pinacidil monohydrate is used in scientific research for studying ATP-sensitive potassium channels, cellular electrophysiology, cell signaling, and neuroscience. It acts as a potassium channel opener.
What are the CAS number and formula for Pinacidil monohydrate?
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The CAS number for Pinacidil monohydrate is 85371-64-8, and its empirical formula is C13H19N5 · H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pinacidil monohydrate as a research-grade chemical. The specific assay or purity is not detailed beyond its designation as a research reagent; it is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for Pinacidil monohydrate?
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Pinacidil monohydrate is classified with a Warning signal word and carries hazard statements including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, such as a dust mask (type N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area and avoid dust formation.
How is Pinacidil monohydrate packed, shipped, and exported?
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Pinacidil monohydrate is carefully packed to maintain its integrity during transit. Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals and laboratory reagents, adhering to all relevant shipping regulations for international distribution.
How can I request a sample or a quote for Pinacidil monohydrate?
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To request a sample or a quote for Pinacidil monohydrate, please visit the Tech Serve Solutions website or contact our sales department directly with your specific requirements.
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